Lavaee Fatemeh, Moqadas Armin, Modarresi Farzan, Nowrouzi Massoumeh
Oral and Dental Disease Research Center, Dept. of Oral and Maxillofacial Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Undergraduate Students, Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
J Dent (Shiraz). 2022 Jun;23(2):113-120. doi: 10.30476/DENTJODS.2021.85691.1145.
There are global efforts for introducing a new herbal antimicrobial agent with minimal side effects. There are some reports about the antimicrobial properties of and .
In this study, the antimicrobial properties of and have been assessed.
In this experimental study, the dental plaque samples were collected from children aged 3 to 5 years old who were referred to a private dental office with diagnosis of dental caries. After determination of the bacterial colonies of , and , the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of ethanolic and methanolic extracts of and were measured by macrodilution and microdilution methods.
The mean MIC and MBC of extract and extract and their combination against , , and were statistically different (< 0.001). The combination of these extracts showed the lowest MIC and MBC.
Hydroalcoholic extracts of the and were effective antibacterial agent against , , and so the combination of these two extracts showed the highest antibacterial properties on all the bacteria evaluated.
全球都在努力引入一种副作用最小的新型草药抗菌剂。有一些关于[未提及具体物质1]和[未提及具体物质2]抗菌特性的报道。
在本研究中,对[未提及具体物质1]和[未提及具体物质2]的抗菌特性进行了评估。
在这项实验性研究中,从一家私人牙科诊所转诊的3至5岁患有龋齿的儿童中收集牙菌斑样本。在确定[未提及具体细菌1]、[未提及具体细菌2]和[未提及具体细菌3]的菌落之后,通过常量稀释法和微量稀释法测量了[未提及具体物质1]和[未提及具体物质2]的乙醇提取物和甲醇提取物的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)。
[未提及具体物质1]提取物、[未提及具体物质2]提取物及其组合对[未提及具体细菌1]、[未提及具体细菌2]和[未提及具体细菌3]的平均MIC和MBC在统计学上有差异(<0.001)。这些提取物的组合显示出最低的MIC和MBC。
[未提及具体物质1]和[未提及具体物质2]的水醇提取物是针对[未提及具体细菌1]、[未提及具体细菌2]和[未提及具体细菌3]的有效抗菌剂,因此这两种提取物的组合对所有评估的细菌显示出最高的抗菌性能。