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四种漱口水对变形链球菌和大肠杆菌的抗菌作用。

The antibacterial effect of four mouthwashes against streptococcus mutans and escherichia coli.

作者信息

Ghapanchi Janan, Lavaee Fatemeh, Moattari Afagh, Shakib Mahmood

机构信息

Department of Oral & Maxillofacial Disease, School of Dentistry, Shiraz, Iran.

Department of Microbiology, School of Medicine, Shiraz, Iran.

出版信息

J Pak Med Assoc. 2015 Apr;65(4):350-3.

Abstract

OBJECTIVE

To evaluate the antimicrobial properties of several mouthwash concentrations on oral Streptococcus mutans and Escherichia coli.

METHODS

The study was conducted at Shiraz Medicine School in 2011. Serial dilutions of Chlorohexidin, Oral B and Persica and Irsha (2,4,8,16,64,128) were prepared in Muller-Hinton media. Minimum inhibitory concentration was visually determined and defined as the lowest concentration of each oral washing which inhibited > 95% growth reduction compared to the growth control well.

RESULTS

Chlorhexidine, Oral B and Irsha mouthwash inhibited Streptococcus mutans even with diluted concentrations. Also, Chlorhexidine and Oral B prohibited Escherichia coli with different potencies. But Persica had no antimicrobial activity against either Escherichia coli or Streptococcus mutans.

CONCLUSIONS

Chlorhexidine, Irsha, and Oral B mouthwashes can be used for antimicrobial effects, especially on Streptococcus mutans. This chemical activity of mouthwashes is an adjuvant for mechanical removing of plaque. However, the antimicrobial effect of Persicaremains controversial.

摘要

目的

评估几种漱口水浓度对口腔变形链球菌和大肠杆菌的抗菌特性。

方法

该研究于2011年在设拉子医学院进行。在Muller-Hinton培养基中制备洗必泰、欧乐B漱口水以及Persica和Irsha漱口水(浓度分别为2、4、8、16、64、128)的系列稀释液。通过肉眼观察确定最低抑菌浓度,其定义为与生长对照孔相比,每种漱口水抑制生长减少>95%的最低浓度。

结果

即使稀释后,洗必泰、欧乐B漱口水和Irsha漱口水也能抑制变形链球菌。此外,洗必泰和欧乐B漱口水对大肠杆菌有不同程度的抑制作用。但Persica漱口水对大肠杆菌和变形链球菌均无抗菌活性。

结论

洗必泰、Irsha漱口水和欧乐B漱口水可用于抗菌,尤其是对变形链球菌。漱口水的这种化学活性是机械清除牙菌斑的辅助手段。然而,Persica漱口水的抗菌效果仍存在争议。

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