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鼻部远端三分之一基底细胞癌的莫氏显微外科手术后的手术结果

Surgical Outcomes Following Mohs Micrographic Surgery for Basal Cell Carcinoma on the Distal Third of the Nose.

作者信息

Fronek Lisa Faye, Dorton David

机构信息

Both authors are with the Department of Dermatology, HCA Healthcare/USF Morsani College of Medicine at Largo Medical Center Program in Largo, Florida.

出版信息

J Clin Aesthet Dermatol. 2022 Jun;15(6):32-36.

Abstract

OBJECTIVE

The primary aim of this study is to determine a quantifiable difference in surgical outcomes between local skin flap, full thickness skin graft (FTSG), and secondary intention (SI) following Mohs micrographic surgery (MMS) for basal cell carcinoma (BCC) on the distal third of the nose.

METHODS

A retrospective chart review of 66 MMS defects on the distal third of the nose performed by a single surgeon between June 2019 to June 2020 was completed. Clinical images of MMS defects and postoperative scars at six months were recorded and measured by the Vancouver Scar Scale (VSS). Pearson Chi-square and Fisher's Exact tests were utilized to determine the relationship between the main predictor variables and VSS.

RESULTS

Of the 66 patients retained, 52 were deemed to have low VSS (77.61%), 11 had medium VSS (16.42%) and three had high VSS (4.48%). Of the 52 patients with low VSS, 40 underwent local flap (76.92%), nine underwent FTSG (17.31%), and three healed by SI (5.77%). Of the 11 patients with medium VSS, two underwent local flap (18.15%), nine underwent FTSG (81.82%), and zero healed by SI. Of the three patients with high VSS, zero underwent local flap or SI, while all three underwent FTSG (100%). Bivariate analysis demonstrated that repair type employed was associated with VSS at six months (<0.0001) with patients treated with local skin flap having better outcomes.

CONCLUSION

Our data illustrate that local skin flaps might result in a lower VSS at six months compared to FTSG or SI, therefore offering superior surgical outcomes in the treatment of BCC on the distal third of the nose.

摘要

目的

本研究的主要目的是确定在鼻远端三分之一处基底细胞癌(BCC)行莫氏显微外科手术(MMS)后,局部皮瓣、全厚皮片移植(FTSG)和二期愈合(SI)之间手术结果的可量化差异。

方法

完成了对一位外科医生在2019年6月至2020年6月期间对鼻远端三分之一处66例MMS缺损进行的回顾性病历审查。通过温哥华瘢痕量表(VSS)记录并测量MMS缺损的临床图像和术后6个月的瘢痕。采用Pearson卡方检验和Fisher精确检验来确定主要预测变量与VSS之间的关系。

结果

在保留的66例患者中,52例被认为VSS低(77.61%),11例VSS中等(16.42%),3例VSS高(4.48%)。在52例VSS低的患者中,40例行局部皮瓣手术(76.92%),9例行FTSG(17.31%),3例通过SI愈合(5.77%)。在11例VSS中等的患者中,2例行局部皮瓣手术(18.15%),9例行FTSG(81.82%),0例通过SI愈合。在3例VSS高的患者中,0例行局部皮瓣手术或SI,而3例均行FTSG(100%)。双变量分析表明,采用的修复类型与6个月时的VSS相关(<0.0001),接受局部皮瓣治疗的患者预后更好。

结论

我们的数据表明,与FTSG或SI相比,局部皮瓣可能在6个月时导致较低的VSS,因此在治疗鼻远端三分之一处的BCC时提供更好的手术结果。

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本文引用的文献

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