Falahatkar Bahram, Poursaeid Samaneh, Sheridan Mark A
Fisheries Department, Faculty of Natural Resources, University of Guilan, Sowmeh Sara, Guilan, Iran.
Department of Marine Sciences, The Caspian Sea Basin Research Center, University of Guilan, Rasht, Guilan, Iran.
Heliyon. 2022 Jun 8;8(6):e09667. doi: 10.1016/j.heliyon.2022.e09667. eCollection 2022 Jun.
The role of growth hormone (GH) in chondrosteans is poorly understood, particularly with regard to its effects on growth. In this study, we examined the influence of exogenous GH on growth performance and body composition in juvenile Siberian sturgeon (). Fish with initial weight of 80.2 ± 0.1 g (mean ± S.E) were injected once every 10 days with either purified ovine GH (oGH) at 1, 2, 4, and 8 μg oGH/g body weight (BW) or with saline over a 50-day period. Treatment with the highest dose of oGH significantly enhanced growth performance (final body weight and length, body weight increase and specific growth rate, SGR). Notably, 8 μg oGH/g BW increased body weight by 33% and SGR by 141% compared to control fish. GH-stimulated (8 μg oGH/g BW) growth was accompanied by increased crude protein content; however, oGH treatment did not affect levels of total protein, total lipid, cholesterol, triglyceride, or glucose in plasma. oGH decreased plasma levels of thyroxine (at 4 μg oGH/g BW), but had no significant effect on plasma levels of triiodothyronine or cortisol compared to controls. These findings indicate that 8 μg oGH/g BW enhances somatic growth and synthesis of body protein in juvenile Siberian sturgeon and demonstrate the feasibility of exogenous oGH treatment in conservation and aquaculture programs for this ancient species.
生长激素（GH）在软骨硬鳞鱼类中的作用尚不清楚，尤其是其对生长的影响。在本研究中，我们检测了外源GH对西伯利亚鲟幼鱼生长性能和身体组成的影响。初始体重为80.2±0.1 g（平均值±标准误）的鱼，在50天内每隔10天注射一次，分别注射1、2、4和8 μg 羊生长激素（oGH）/g体重的纯化oGH或生理盐水。最高剂量oGH处理显著提高了生长性能（终末体重和体长、体重增加和特定生长率，SGR）。值得注意的是，与对照鱼相比，8 μg oGH/g体重使体重增加了33%，SGR提高了141%。GH刺激（8 μg oGH/g体重）的生长伴随着粗蛋白含量的增加；然而，oGH处理对血浆中总蛋白、总脂质、胆固醇、甘油三酯或葡萄糖水平没有影响。oGH降低了血浆甲状腺素水平（4 μg oGH/g体重时），但与对照组相比，对血浆三碘甲状腺原氨酸或皮质醇水平没有显著影响。这些发现表明，8 μg oGH/g体重可促进西伯利亚鲟幼鱼的体细胞生长和身体蛋白质合成，并证明了外源oGH处理在这种古老物种的保护和水产养殖计划中的可行性。
