Wang Xingjie, Ma Kaikai, Goh Teffanie, Mian Mohammad Rasel, Xie Haomiao, Mao Haochuan, Duan Jiaxin, Kirlikovali Kent O, Stone Aaron E B S, Ray Debmalya, Wasielewski Michael R, Gagliardi Laura, Farha Omar K
International Institute for Nanotechnology, Institute for Sustainability and Energy at Northwestern, and Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.
Department of Chemistry, Pritzker School of Molecular Engineering, James Franck Institute, University of Chicago, 5735 S Ellis Avenue, Chicago, Illinois 60637, United States.
J Am Chem Soc. 2022 Jul 13;144(27):12192-12201. doi: 10.1021/jacs.2c03060. Epub 2022 Jul 5.
The world is currently suffering socially, economically, and politically from the recent pandemic outbreak due to the coronavirus disease 2019 (COVID-19), and those in hospitals, schools, and elderly nursing homes face enhanced threats. Healthcare textiles, such as masks and medical staff gowns, are susceptible to contamination of various pathogenic microorganisms, including bacteria and viruses. Metal-organic frameworks (MOFs) can potentially address these challenges due to their tunable reactivity and ability to be incorporated as porous coatings on textile materials. Here, we report how incorporating titanium into the zirconium-pyrene-based MOF NU-1000, denoted as , generates a highly reactive biocidal photocatalyst. This MOF features a rare ligand migration phenomenon, and both the Ti/Zr center and the pyrene linker act synergistically as dual active centers and widen the absorption band for this material, which results in enhanced reactive oxygen species generation upon visible light irradiation. Additionally, we found that the ligand migration process is generally applicable to other topology Zr-MOFs. Importantly, can be easily incorporated onto cotton textile cloths as a coating, and the resulting composite material demonstrates fast and potent biocidal activity against Gram-negative bacteria (), Gram-positive bacteria (), and T7 bacteriophage virus with up to a 7-log(99.99999%) reduction within 1 h under simulated daylight.
由于2019年冠状病毒病（COVID-19）最近的大流行爆发，世界目前在社会、经济和政治方面都遭受着痛苦，医院、学校和老年疗养院的人们面临着更大的威胁。医疗用纺织品，如口罩和医护人员的工作服，容易受到包括细菌和病毒在内的各种致病微生物的污染。金属有机框架（MOF）因其可调谐的反应性以及能够作为多孔涂层结合到纺织材料上的能力，有可能应对这些挑战。在此，我们报告了将钛掺入基于锆-芘的MOF NU-1000（表示为 ）如何产生一种高活性的杀菌光催化剂。这种MOF具有罕见的配体迁移现象，Ti/Zr中心和芘连接体都作为双活性中心协同起作用，并拓宽了该材料的吸收带，这导致在可见光照射下产生更多的活性氧物种。此外，我们发现配体迁移过程通常适用于其他 拓扑结构的Zr-MOFs。重要的是， 可以很容易地作为涂层结合到棉纺织布上，所得复合材料在模拟日光下1小时内对革兰氏阴性菌（ ）、革兰氏阳性菌（ ）和T7噬菌体病毒表现出快速而有效的杀菌活性，细菌减少率高达7个对数（99.99999%）。
