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30-60 岁患者股骨近端骨折固定失败后行骨水泥型关节置换的假体生存率:一项中位随访 10 年的回顾性研究。

Implant survival of cemented arthroplasty following failed fixation of proximal femoral fractures in patients aged 30-60 years: a retrospective study with a median follow-up of 10 years.

机构信息

Department of Anesthesiology, Wuhan Fourth Hospital, No.473, Hanzheng Street, Qiaokou District, Wuhan, 430033, China.

Department of Traditional Chinese Medicine, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Yuexiu District, Guangzhou, 510080, China.

出版信息

BMC Musculoskelet Disord. 2022 Jul 4;23(1):637. doi: 10.1186/s12891-022-05587-0.

Abstract

BACKGROUND

Given the unremitting growth in the volume of failed fixations of proximal femoral fractures (PFFs) in recent years, it is predictable that total hip replacements (THRs) will be the preferred surgical procedure. The long-term survival of cemented THR (CTHR) revisions remains controversial in patients aged 30-60 years. The goal of this retrospective review was to evaluate the 10-year survival of CTHRs following prior failed primary fixations of PFFs in patients aged 30-60 years.

METHODS

We retrospectively identified CTHR revisions implemented at four medical centres during 2008-2017 for a failed primary fixation of PFFs in consecutive patients aged 30-60 years. The primary endpoint was implant survival calculated using the Kaplan-Meier method with 95% confidence intervals (CIs); secondary endpoints included functional scores assessed by Harris hip scores (HHS) and main revision-related orthopaedic complications. Follow-up was executed at 1, 2, 3, and 8 years following revision and then at 1-year intervals until the revision, death, or study deadline, whichever occurred first.

RESULTS

In total, 120 patients (120 hips) who met the eligibility criteria were eligible for follow-up. The median follow-up was 10.2 years (range, 8-12 years). Kaplan-Meier survivorship showed that implant survival with revision for any reason as the endpoint was 95% at 5 years (CI: 93-97%), 89% at 8 years (CI: 86-92%), and 86% at 10 years (CI: 83-89%). Patients treated with three hollow screws had better revision-free survival than patients treated with proximal femoral nail antirotation (PFNA), dynamic hip screw (DHS) or titanium plate plus screws (three p < 0.05). Functional scores were apt to decrease gradually, and at the final follow-up, the mean HHS was 76.9 (range, 67.4-86.4). The overall rate of main revision-related orthopaedic complications was 18.3% (22/120).

CONCLUSION

CTHR implemented following prior failed primary fixations of PFFs tends to afford an acceptable 10-year survival, along with advantageous HHS and a low rate of main revision-related orthopaedic complications, which may support an inclination to follow the utilisation of CTHRs, especially in revision settings for intracapsular fractures.

摘要

背景

近年来,股骨近端骨折(PFF)固定失败的数量不断增加,可以预见全髋关节置换术(THR)将成为首选手术。30-60 岁患者骨水泥型 THR(CTHR)翻修的长期存活率仍存在争议。本回顾性研究的目的是评估 30-60 岁患者先前 PFF 初次固定失败后行 CTHR 的 10 年存活率。

方法

我们回顾性地确定了 2008-2017 年期间四个医疗中心对连续 30-60 岁患者先前 PFF 初次固定失败后行 CTHR 翻修的情况。主要终点是使用 Kaplan-Meier 法计算的植入物存活率,置信区间(CI)为 95%;次要终点包括 Harris 髋关节评分(HHS)评估的功能评分和主要与翻修相关的骨科并发症。在翻修后 1、2、3 和 8 年进行随访,然后每隔 1 年随访一次,直到翻修、死亡或研究截止日期,以先发生者为准。

结果

共有 120 名符合入选标准的患者(120 髋)纳入随访。中位随访时间为 10.2 年(范围:8-12 年)。Kaplan-Meier 生存分析显示,以任何原因翻修为终点的植入物存活率为 5 年时 95%(CI:93-97%),8 年时 89%(CI:86-92%),10 年时 86%(CI:83-89%)。用三根空心螺钉治疗的患者比用股骨近端髓内钉抗旋转(PFNA)、动力髋螺钉(DHS)或钛板加螺钉治疗的患者(p<0.05)无翻修生存率更高。功能评分逐渐下降,末次随访时,平均 HHS 为 76.9(范围:67.4-86.4)。主要与翻修相关的骨科并发症总体发生率为 18.3%(22/120)。

结论

对于先前 PFF 初次固定失败的患者,行 CTHR 治疗后,10 年存活率较高,HHS 评分较高,与翻修相关的主要骨科并发症发生率较低,这可能支持使用 CTHR 的倾向,特别是在囊内骨折的翻修中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d42e/9252004/518560ced443/12891_2022_5587_Fig1_HTML.jpg

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