Melman Yacob, Katz Evgeny, Smutok Oleh
Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY 13699, USA.
Chemphyschem. 2022 Oct 19;23(20):e202200352. doi: 10.1002/cphc.202200352. Epub 2022 Jul 26.
Concatenated enzyme-based Boolean logic gates activated with 5 chemical input signals were analyzed with a smartphone photo camera. Simultaneous detection of 32 input combinations was conveniently performed using enzyme-modified fiberglass sensing spots generating fluorescence with different intensities for the 0 and 1 binary outputs. The developed technology offers an easy readout method for multi-channel logic systems.
利用智能手机摄像头对由5种化学输入信号激活的串联酶基布尔逻辑门进行了分析。使用酶修饰的玻璃纤维传感点方便地同时检测32种输入组合,这些传感点为0和1二进制输出产生不同强度的荧光。所开发的技术为多通道逻辑系统提供了一种易于读出的方法。