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催眠生物组学:催眠治疗肠易激综合征的新的、潜在前沿领域——文献述评。

Hypnobiome: A New, Potential Frontier of Hypnotherapy in the Treatment of Irritable Bowel Syndrome-A Narrative Review of the Literature.

机构信息

Interdepartmental Pain Center, Department of Neurosurgery, University of Milano, Italy.

出版信息

Int J Clin Exp Hypn. 2022 Jul-Sep;70(3):286-299. doi: 10.1080/00207144.2022.2094269. Epub 2022 Jul 6.

DOI:10.1080/00207144.2022.2094269
PMID:35792903
Abstract

Increasing evidence suggests that the gut-brain axis may play a key role in health and disease via a bidirectional communication network involving neural and immunoendocrine pathways. This complex interplay deeply influences both gut microbiota and brain behavior. Pathobiome or gut dysbiosis is relevant for the pathogenesis of functional gastrointestinal disorders, such as IBS, chronic pain syndromes, and neurological and mental disorders. As a consequence, targeting the gut microbiota is emerging as a novel, effective therapeutic perspective. Among many treatment options, psychological interventions, including hypnosis, have been used to target the so-called psychobiome and its hypnotic analogue, i.e., hypnobiome, referring to their potential efficacy to modulate the mind-gut axis in IBS patients. A narrative review of the recent literature is provided and circumstantial evidence suggests that hypnobiome may represent a new promising frontier of hypnotherapy.

摘要

越来越多的证据表明,通过涉及神经和免疫内分泌途径的双向通讯网络,肠道-大脑轴可能在健康和疾病中发挥关键作用。这种复杂的相互作用深刻地影响了肠道微生物群和大脑行为。 病理生物群或肠道菌群失调与功能性胃肠疾病(例如 IBS、慢性疼痛综合征以及神经和精神疾病)的发病机制有关。 因此,针对肠道微生物群已成为一种新的有效治疗方法。 在许多治疗选择中,包括催眠在内的心理干预措施已被用于针对所谓的心理生物群及其催眠类似物(即,催眠生物群),这是指它们在调节 IBS 患者的“脑-肠轴”方面的潜在功效。 对最近文献的叙述性综述表明,催眠生物群可能代表了催眠治疗的一个新的有前途的前沿领域。

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Hypnobiome: A New, Potential Frontier of Hypnotherapy in the Treatment of Irritable Bowel Syndrome-A Narrative Review of the Literature.催眠生物组学:催眠治疗肠易激综合征的新的、潜在前沿领域——文献述评。
Int J Clin Exp Hypn. 2022 Jul-Sep;70(3):286-299. doi: 10.1080/00207144.2022.2094269. Epub 2022 Jul 6.
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J Educ Health Promot. 2025 Mar 28;14:107. doi: 10.4103/jehp.jehp_1924_23. eCollection 2025.
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Impact of Enteric Nervous Cells on Irritable Bowel Syndrome: Potential Treatment Options.肠神经细胞对肠易激综合征的影响:潜在治疗选择
Microorganisms. 2024 Oct 9;12(10):2036. doi: 10.3390/microorganisms12102036.
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Physiological Correlates of Hypnotizability: Hypnotic Behaviour and Prognostic Role in Medicine.
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Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment.肠易激综合征:流行病学、重叠障碍、病理生理学和治疗。
World J Gastroenterol. 2023 Jul 14;29(26):4120-4135. doi: 10.3748/wjg.v29.i26.4120.
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Hypnotherapy and IBS: Implicit, long-term stress memory in the ENS?催眠疗法与肠易激综合征:肠神经系统中存在内隐的长期应激记忆?
Heliyon. 2022 Dec 30;9(1):e12751. doi: 10.1016/j.heliyon.2022.e12751. eCollection 2023 Jan.