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肠易激综合征：流行病学、重叠障碍、病理生理学和治疗。

Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment.

机构信息

Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.

Institute of Digestive Diseases, Beijing Institute of Spleen and Stomach Disease of Traditional Chinese Medicine, Beijing 100091, China.

出版信息

World J Gastroenterol. 2023 Jul 14;29(26):4120-4135. doi: 10.3748/wjg.v29.i26.4120.

DOI:10.3748/wjg.v29.i26.4120
PMID:37475846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10354571/
Abstract

Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disease with a significant impact on patients' quality of life and a high socioeconomic burden. And the understanding of IBS has changed since the release of the Rome IV diagnosis in 2016. With the upcoming Rome V revision, it is necessary to review the results of IBS research in recent years. In this review of IBS, we can highlight future concerns by reviewing the results of IBS research on epidemiology, overlap disorders, pathophysiology, and treatment over the past decade and summarizing the latest research.

摘要

肠易激综合征（IBS）是一种常见的慢性胃肠道疾病，对患者的生活质量有重大影响，且具有较高的社会经济负担。自 2016 年罗马 IV 诊断标准发布以来，人们对 IBS 的认识发生了变化。随着即将到来的罗马 V 修订版，有必要对近年来 IBS 的研究结果进行回顾。在这篇 IBS 综述中，我们可以通过回顾过去十年中 IBS 在流行病学、重叠疾病、病理生理学和治疗方面的研究结果，并总结最新的研究，突出未来的关注点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/7b2e53ac6667/WJG-29-4120-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/188e84576527/WJG-29-4120-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/08de6844fe73/WJG-29-4120-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/b61c3cf8f369/WJG-29-4120-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/d9e7e065484a/WJG-29-4120-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/7b2e53ac6667/WJG-29-4120-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/188e84576527/WJG-29-4120-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/08de6844fe73/WJG-29-4120-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/b61c3cf8f369/WJG-29-4120-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/d9e7e065484a/WJG-29-4120-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd22/10354571/7b2e53ac6667/WJG-29-4120-g005.jpg

相似文献

[1]
Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment.

World J Gastroenterol. 2023-7-14

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
[Irritable bowel syndrome in the Russian Federation: results of the ROMERUS multicenter observational study].

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引用本文的文献

[1]
Imaging findings of irritable bowel syndrome patients, and the diagnostic value of irritable bowel syndrome: A systematic review.

World J Methodol. 2025-12-20

[2]
PDE4 inhibitor apremilast ameliorates TNBS-induced irritable bowel syndrome in mice by activating the Nrf-2 signaling pathway in enteric glial cells.

Acta Pharmacol Sin. 2025-9-1

[3]
Unraveling functional neurological disorder in pediatric populations: A systematic review of diagnosis, treatment, and outcomes.

World J Clin Pediatr. 2025-9-9

[4]
The Relationship of Dietary Nutrient Patterns and Irritable Bowel Syndrome: A Multicenter Case-Control Study.

Food Sci Nutr. 2025-8-19

[5]
Demographic and Clinical Epidemiology of Irritable Bowel Syndrome in U.S. Community Health Centers: A Cross-Sectional Analysis of the 2022-2023 National Ambulatory Medical Care Survey.

Cureus. 2025-7-1

[6]
Combination therapy with otilonium bromide and trimebutine maleate demonstrates significant clinical advantages in irritable bowel syndrome patients.

Am J Transl Res. 2025-6-15

[7]
Sentiment analysis and topic modeling of social media data to explore public discourse on irritable bowel syndrome.

Sci Rep. 2025-7-1

[8]
Therapeutic Potential of Flavonoids and Flavonoid-Rich Compounds in Irritable Bowel Syndrome.

Drug Des Devel Ther. 2025-6-6

[9]
Breaking the cycle: Psychological and social dimensions of pediatric functional gastrointestinal disorders.

World J Clin Pediatr. 2025-6-9

[10]
Targeted probiotic therapy in irritable bowel syndrome: a clinical evaluation on CBM588 and W11.

Front Med (Lausanne). 2025-5-20

本文引用的文献

[1]
Constipation-Predominant Irritable Bowel Syndrome (IBS-C): Effects of Different Nutritional Patterns on Intestinal Dysbiosis and Symptoms.

Nutrients. 2023-3-28

[2]
Irritable bowel syndrome: treatment based on pathophysiology and biomarkers.

Gut. 2023-3

[3]
The promotion mechanism of prebiotics for probiotics: A review.

Front Nutr. 2022-10-5

[4]
Spinal CircKcnk9 Regulates Chronic Visceral Hypersensitivity of Irritable Bowel Syndrome.

J Pain. 2023-3

[5]
Probiotics therapy for adults with diarrhea-predominant irritable bowel syndrome: a systematic review and meta-analysis of 10 RCTs.

Int J Colorectal Dis. 2022-11

[6]
Associations of Fecal Short Chain Fatty Acids With Colonic Transit, Fecal Bile Acid, and Food Intake in Irritable Bowel Syndrome.

Clin Transl Gastroenterol. 2023-1-1

[7]
Associations between postprandial symptoms, hydrogen and methane production, and transit time in irritable bowel syndrome.

Neurogastroenterol Motil. 2023-2

[8]
Encapsulation of multiple probiotics, synbiotics, or nutrabiotics for improved health effects: A review.

Adv Colloid Interface Sci. 2022-11

[9]
Effect and Mechanism of Flavored Tongxie Yaofang Decoction for Diarrheal Irritable Bowel Syndrome under Intestinal Microecology.

Evid Based Complement Alternat Med. 2022-8-3

[10]
Prevalence, epidemiology and associated healthcare burden of Rome IV irritable bowel syndrome and functional dyspepsia in the adult population of Gibraltar.

BMJ Open Gastroenterol. 2022-8

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