氨苯砜作为浅表性天疱疮的初始治疗。9例报告。

Dapsone as initial treatment in superficial pemphigus. Report of nine cases.

作者信息

Basset N, Guillot B, Michel B, Meynadier J, Guilhou J J

出版信息

Arch Dermatol. 1987 Jun;123(6):783-5.

Abstract

Nine cases of superficial pemphigus that were treated by dapsone as the initial mode of therapy are reported. Five patients, all having low or negative serum anti-intercellular cement substance antibody titers, responded dramatically, while the other four patients, showing high titers of anti-intercellular cement substance antibodies, did not respond to this treatment. Complications of therapy were observed in three cases.

摘要

报告了9例以氨苯砜作为初始治疗方式的浅表性天疱疮病例。5例患者血清抗细胞间黏附物质抗体滴度低或为阴性，治疗反应显著，而另外4例患者抗细胞间黏附物质抗体滴度高，对该治疗无反应。3例观察到治疗并发症。