Bystryn J C
Arch Dermatol. 1984 Jul;120(7):941-51.
The effectiveness of adjuvant therapy of pemphigus was evaluated by comparing the results of studies of pemphigus treated with corticosteroids and adjuvant as opposed to corticosteroids only. There has been a steady and striking improvement in the prognosis of pemphigus during the past three decades. However, factors other than the use of adjuvant therapy appear to be responsible, since the survival and incidence of remissions in patients treated with adjuvants was only slightly better than that of patients treated with corticosteroids alone. The variable course of pemphigus and the lack of stratification makes it difficult to judge whether these slight differences have any relevance. A suggested protocol to treat pemphigus is presented.
通过比较使用皮质类固醇和辅助药物治疗天疱疮与仅使用皮质类固醇治疗天疱疮的研究结果，评估了天疱疮辅助治疗的有效性。在过去三十年中，天疱疮的预后有了稳步且显著的改善。然而，似乎是其他因素而非辅助治疗的使用起了作用，因为接受辅助治疗的患者的生存率和缓解率仅略高于仅接受皮质类固醇治疗的患者。天疱疮病程多变且缺乏分层，这使得判断这些细微差异是否有意义变得困难。本文提出了一个治疗天疱疮的建议方案。
