Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
School for Oncology and Developmental Biology-GROW, Maastricht University Medical Center, Maastricht, The Netherlands.
Dysphagia. 2023 Feb;38(1):127-144. doi: 10.1007/s00455-022-10484-8. Epub 2022 Jul 7.
Oropharyngeal dysphagia (OD) is a high impact morbidity in head-and-neck cancer (HNC) patients. A wide variety of instruments are developed to screen for affective symptoms and OD. The current paper aims to systematically review and appraise the literature to obtain insight into the prevalence, strength, and causal direction of the relationship between affective symptoms and OD in HNC patients. This review was conducted in accordance with the PRISMA statement. A systematic search of the literature was performed using PubMed, PsycINFO, Cochrane, and Embase. All available publications reporting on the relationship between affective conditions and swallowing function in HNC patients were included. Conference papers, tutorials, reviews, and studies with less than 5 patients were excluded. Fifteen studies met the inclusion criteria. The level of evidence and methodological quality were assessed using the ABC-rating scale and QualSyst critical appraisal tool. Eleven studies reported a positive relationship between affective symptoms and OD. The findings of this paper highlight the importance of affective symptom screening in dysphagic HNC patients as clinically relevant affective symptoms and OD seems to be prevalent and coincident in this population. Considering the impact of affective symptoms and OD on patients' daily life, early detection and an integrated interdisciplinary approach are recommended. However, due to the heterogeneity of study designs, outcomes, and outcome measures, the generalization of study results is limited.
口咽吞咽困难（OD）是头颈部癌症（HNC）患者的高发病率。开发了各种仪器来筛查情感症状和 OD。本研究旨在系统地回顾和评估文献，以深入了解 HNC 患者情感症状与 OD 之间的关系的普遍性、强度和因果关系。本综述符合 PRISMA 声明。使用 PubMed、PsycINFO、Cochrane 和 Embase 进行了系统的文献搜索。纳入了所有报告 HNC 患者情感状况与吞咽功能之间关系的可用出版物。排除了会议论文、教程、综述和患者少于 5 人的研究。有 15 项研究符合纳入标准。使用 ABC 评分量表和 QualSyst 批判性评估工具评估证据水平和方法学质量。11 项研究报告了情感症状与 OD 之间存在正相关关系。本文的研究结果强调了在吞咽困难的 HNC 患者中进行情感症状筛查的重要性，因为在该人群中，临床相关的情感症状和 OD 似乎很普遍且同时存在。考虑到情感症状和 OD 对患者日常生活的影响，建议早期发现和采用综合的跨学科方法。然而，由于研究设计、结果和测量结果的异质性，研究结果的推广受到限制。
