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接种ChAdOx1 nCoV-19疫苗后出现眼部症状的重症肌无力:一例报告

Myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccination: A case report.

作者信息

Kang Min Chae, Park Kyung-Ah, Min Ju-Hong, Oh Sei Yeul

机构信息

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

出版信息

Am J Ophthalmol Case Rep. 2022 Jun 25;27:101620. doi: 10.1016/j.ajoc.2022.101620. eCollection 2022 Sep.

Abstract

PURPOSE

We report on the case of a 35-year-old man who developed myasthenia gravis with ocular symptoms following a ChAdOx1 nCoV-19 vaccine injection.

OBSERVATIONS

A 35-year-old man complained of binocular diplopia one month following ChAdOx1 nCoV-19 vaccination. He had weak infraduction of the left eye. Upper and lower extremity strength was normal on presentation. A serum antiacetylcholine receptor antibody titer was elevated at 1.60 nmol/L. His diplopia improved temporarily following the application of an ice pack for 2 min.

CONCLUSIONS AND IMPORTANCE

This case report describes a rare occurrence of myasthenia gravis with ocular symptoms as a potential complication of ChAdOx1 nCoV-19 vaccination.

摘要

目的

我们报告一例35岁男性在接种ChAdOx1 nCoV-19疫苗后出现伴有眼部症状的重症肌无力病例。

观察结果

一名35岁男性在接种ChAdOx1 nCoV-19疫苗后一个月出现双眼复视。他左眼的下转功能减弱。就诊时上肢和下肢力量正常。血清抗乙酰胆碱受体抗体滴度升高至1.60 nmol/L。冰敷2分钟后他的复视症状暂时改善。

结论及重要性

本病例报告描述了接种ChAdOx1 nCoV-19疫苗后罕见出现的伴有眼部症状的重症肌无力,这是一种潜在并发症。

相似文献

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Myasthenia Gravis Presenting after Administration of the mRNA-1273 Vaccine.接种mRNA-1273疫苗后出现的重症肌无力。
Eur J Case Rep Intern Med. 2022 Jul 12;9(7):003439. doi: 10.12890/2022_003439. eCollection 2022.

本文引用的文献

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A Case of COVID-19 Vaccine Associated New Diagnosis Myasthenia Gravis.COVID-19 疫苗相关新诊断重症肌无力病例报告。
J Prim Care Community Health. 2021 Jan-Dec;12:21501327211051933. doi: 10.1177/21501327211051933.
8
Ocular adverse events following vaccination: overview and update.接种疫苗后的眼部不良事件:概述和更新。
Surv Ophthalmol. 2022 Mar-Apr;67(2):293-306. doi: 10.1016/j.survophthal.2021.04.001. Epub 2021 Apr 16.

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