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成年男性睡眠不佳与肥胖相关的代谢紊乱

Poor sleep and the metabolic derangements associated with obesity in adult males.

作者信息

Ankita Annu, Mehta Bharati, Dutt Naveen, Nayak Prasunpriya, Sharma Praveen

机构信息

Department of Physiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Department of Pulmonary Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

出版信息

J Family Med Prim Care. 2022 May;11(5):2026-2031. doi: 10.4103/jfmpc.jfmpc_1787_21. Epub 2022 May 14.

DOI:10.4103/jfmpc.jfmpc_1787_21
PMID:35800495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9254843/
Abstract

CONTEXT

Short sleep and obesity have a causal association with each other. Obesity is also associated with metabolic imbalances. However, a subset of 20%-30% of obese population have only few metabolic complications, known as metabolically healthy obese (MHO) and rest with worsened metabolic profile are known as metabolically abnormal obese (MAO).

AIMS

To find the association between sleep quality and metabolic health of adult obese males.

SETTINGS AND DESIGN

The study was a cross-sectional study conducted at medicine out-patient department of the institute.

METHODS AND MATERIAL

In this study, hundred adult obese males of age group 25-60 years, with Body mass index (BMI) ≥ 25 Kg/m, were divided into MHO and MAO, based on their metabolic health using Joint Interim criteria. Sleep quality was assessed using Pittsburgh sleep questionnaire index (PSQI).

STATISTICAL ANALYSIS USED

The data obtained were analyzed using PAST statistical software.

RESULTS

The two groups MHO and MAO presented with significant differences in their mean age and BMI ( = 0.0001). The global score of PSQI was significantly high for MAO than MHO with mean values of 8.24 ± 3.60 and 6.65 ± 3.58, respectively ( = 0.016). Sleep disturbances score was significantly high in MAO ( = 0.0001). Significant associations were observed for global score with age, BMI, waist circumference, fasting blood sugar, and triglycerides.

CONCLUSIONS

Poor sleep quality was significantly associated with detrimental metabolic profile and BMI. The metabolic health worsened with increasing age and obesity.

摘要

背景

睡眠不足与肥胖之间存在因果关系。肥胖还与代谢失衡有关。然而,20%-30%的肥胖人群只有很少的代谢并发症,被称为代谢健康肥胖(MHO),其余代谢状况恶化的则被称为代谢异常肥胖(MAO)。

目的

探讨成年肥胖男性睡眠质量与代谢健康之间的关系。

设置与设计

本研究为在该研究所门诊部进行的横断面研究。

方法与材料

在本研究中,根据联合临时标准,将100名年龄在25-60岁、体重指数(BMI)≥25 Kg/m²的成年肥胖男性,根据其代谢健康状况分为MHO和MAO两组。使用匹兹堡睡眠问卷指数(PSQI)评估睡眠质量。

所用统计分析

使用PAST统计软件对获得的数据进行分析。

结果

MHO和MAO两组在平均年龄和BMI方面存在显著差异(P = 0.0001)。MAO组的PSQI全球评分显著高于MHO组,平均值分别为8.24±3.60和6.65±3.58(P = 0.016)。MAO组的睡眠障碍评分显著较高(P = 0.0001)。观察到全球评分与年龄、BMI、腰围、空腹血糖和甘油三酯之间存在显著关联。

结论

睡眠质量差与不良的代谢状况和BMI显著相关。随着年龄增长和肥胖程度增加,代谢健康状况恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/11f01ebdda47/JFMPC-11-2026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/b7234c833f72/JFMPC-11-2026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/d48a8c905561/JFMPC-11-2026-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/11f01ebdda47/JFMPC-11-2026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/b7234c833f72/JFMPC-11-2026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/d48a8c905561/JFMPC-11-2026-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0198/9254843/11f01ebdda47/JFMPC-11-2026-g003.jpg

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