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开发一种经过验证的糖尿病风险图表作为一种简单的工具,用于预测印度尼西亚茂物市糖尿病的发病。

Development of a Validated Diabetes Risk Chart as a Simple Tool to Predict the Onset of Diabetes in Bogor, Indonesia.

机构信息

National Institute of Health Research and Development (NIHRD), The Ministry of Health of Republic of Indonesia.

出版信息

J ASEAN Fed Endocr Soc. 2022;37(1):46-52. doi: 10.15605/jafes.037.01.09. Epub 2022 Apr 27.

DOI:10.15605/jafes.037.01.09
PMID:35800598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9242663/
Abstract

OBJECTIVE

To develop a simple, non-invasive tool for predicting the onset of type 2 diabetes mellitus (T2DM). Methodology. A total of 4418 nondiabetic respondents living in Bogor were included in this cohort study. Their ages ranged from 25 to 60 years old and were followed for 6 years with interviews, physical examinations and laboratory tests. The investigators used logistic regression to create a tool for diabetes risk determination.

RESULTS

The cumulative incidence of T2DM was 17.9%. Risk factors significantly associated with T2DM included age, obesity, central obesity, hypertension and lack of physical activity. The Bogor Diabetes Risk Prediction (BDRP) chart had a cut-off of 0.128, with sensitivity of 76.6% and specificity of 50.3%. The Positive Predictive Value (PPV) was 21.6% and Negative Predictive Value (NPV) was 92.3%. The Area under the Curve (AUC) was 0.70 with a 95% confidence interval ranging from 0.675-0.721.

CONCLUSION

The BDRP chart is a simple and non-invasive tool to predict T2DM. In addition, the BDRP chart is reliable and can be easily used in primary health care.

摘要

目的

开发一种简单、无创的工具,用于预测 2 型糖尿病(T2DM)的发病。

方法

本队列研究共纳入 4418 名居住在茂物的非糖尿病患者。他们的年龄在 25 至 60 岁之间,随访 6 年,通过访谈、体检和实验室检查进行随访。研究人员使用逻辑回归创建了一种用于确定糖尿病风险的工具。

结果

T2DM 的累积发病率为 17.9%。与 T2DM 显著相关的危险因素包括年龄、肥胖、中心性肥胖、高血压和缺乏身体活动。茂物糖尿病风险预测(BDRP)图表的截断值为 0.128,灵敏度为 76.6%,特异性为 50.3%。阳性预测值(PPV)为 21.6%,阴性预测值(NPV)为 92.3%。曲线下面积(AUC)为 0.70,95%置信区间为 0.675-0.721。

结论

BDRP 图表是一种简单、无创的预测 T2DM 的工具。此外,BDRP 图表可靠,可在初级保健中轻松使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/5b6957bc905f/JAFES-37-1-46-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/b1767b348067/JAFES-37-1-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/ce52fef00f31/JAFES-37-1-46-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/5b6957bc905f/JAFES-37-1-46-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/b1767b348067/JAFES-37-1-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/ce52fef00f31/JAFES-37-1-46-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3af/9242663/5b6957bc905f/JAFES-37-1-46-g003.jpg

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