Hsu Pei-Yu, Wu En-Bo
Department of Anesthesiology, China Medical University Hospital, China Medical University, Taichung 404, Taiwan.
Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
World J Clin Cases. 2022 May 26;10(15):5111-5118. doi: 10.12998/wjcc.v10.i15.5111.
Acute pulmonary embolism (APE) is a rare and potentially life-threatening condition, even with early detection and prompt management. Intraoperative APE required specific ways for detecting since classic symptoms of APE in the awake patient could not be observed or self-reported by the patient under general anesthesia.
A 44-year-old man with a history of hepatic cell carcinoma was admitted for radical nephrectomy and tumor thrombectomy due to a newly found kidney tumor with inferior vena cava (IVC) tumor thrombus. APE that occurred during tumor thrombectomy with hypercapnia and desaturation. The capnography combined with the transesophageal echocardiography (TEE) provided a crucial differential diagnosis during the operation. The patient was continuously managed with aggressive intravenous fluid resuscitation and blood transfusion under continuous cardiac output monitoring to maintain hemodynamic stability. He completed the surgery under stable hemodynamics and was extubated after percutaneous mechanical thrombectomy by a certified cardiologist. There were no significant symptoms and signs or obvious discomfort in the patient's self-report during visits to the general ward.
Under general anesthesia for IVC tumor thrombus surgery, a sudden decrease in end-tidal carbon dioxide is the initial indicator of APE, which occurs before hemodynamic changes. When intraoperative APE is suspected, TEE is useful in the diagnosis and monitoring before computer tomography pulmonary angiogram. Timely clinical impression and supportive treatment and intervention should be conducted to obtain a better prognosis.
急性肺栓塞(APE)是一种罕见且可能危及生命的疾病,即使早期发现并及时处理亦是如此。术中发生的APE需要采用特定的检测方法,因为清醒患者中APE的典型症状在全身麻醉下无法被观察到或由患者自我报告。
一名44岁有肝细胞癌病史的男性因新发现的肾肿瘤伴下腔静脉(IVC)肿瘤血栓而入院接受根治性肾切除术和肿瘤血栓切除术。在肿瘤血栓切除术中发生了伴有高碳酸血症和血氧饱和度降低的APE。术中二氧化碳描记法联合经食管超声心动图(TEE)提供了关键的鉴别诊断。在持续心输出量监测下,对患者持续进行积极的静脉补液复苏和输血以维持血流动力学稳定。他在血流动力学稳定的情况下完成了手术,并在一名专业心脏病专家进行经皮机械血栓清除术后拔管。在普通病房就诊期间,患者自我报告无明显症状、体征或明显不适。
在全身麻醉下行IVC肿瘤血栓手术时,呼气末二氧化碳突然下降是APE的初始指标,其发生在血流动力学变化之前。当怀疑术中发生APE时,在计算机断层扫描肺动脉造影之前,TEE有助于诊断和监测。应及时进行临床判断并给予支持性治疗和干预以获得更好的预后。