Madjarov Joana, Soares Ricardo, Paquete Catarina M, Louro Ricardo O
Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Instituto Nacional de Investigação Agrária e Veterinária, Oeiras, Portugal.
Front Microbiol. 2022 Jun 20;13:913311. doi: 10.3389/fmicb.2022.913311. eCollection 2022.
is a bacterium that can accept electrons from cathodes to drive microbial electrosynthesis (MES) of acetate from carbon dioxide. It is the biocatalyst with the highest acetate production rate described. Here we review the research on across different disciplines, including microbiology, biochemistry, engineering, and materials science, to summarize and assess the state-of-the-art. The improvement of the biocatalytic capacity of in the last 10 years, using different optimization strategies is described and discussed. In addition, we propose possible electron uptake routes derived from genetic and experimental data described in the literature and point out the possibilities to understand and improve the performance of through genetic engineering. Finally, we identify current knowledge gaps guiding further research efforts to explore this promising organism for the MES field.
是一种能够从阴极接受电子以驱动由二氧化碳进行微生物电合成乙酸盐（MES）的细菌。它是所描述的乙酸盐生产率最高的生物催化剂。在此，我们综述了跨不同学科，包括微生物学、生物化学、工程学和材料科学对其的研究，以总结和评估当前的技术水平。描述并讨论了在过去10年中使用不同优化策略对其生物催化能力的提升。此外，我们根据文献中描述的遗传和实验数据提出了可能的电子摄取途径，并指出了通过基因工程理解和改善其性能的可能性。最后，我们确定了当前的知识空白，以指导进一步的研究工作，从而为MES领域探索这种有前景的生物体。
