Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University, 70-204 Szczecin, Poland.
Int J Environ Res Public Health. 2022 Jun 21;19(13):7576. doi: 10.3390/ijerph19137576.
The aim of this study was to analyze the relationship between the prevalence of erectile dysfunction in men as diagnosed by the International Index of Erectile Function (IIEF) questionnaire and the respective levels of sex hormones and biochemical parameters, as well as indices of visceral fat accumulation and activity.
The study comprised 148 male (60-75 years) patients from primary care outpatient clinics in the city of Szczecin (Poland). The men were asked to complete a shortened survey questionnaire with sociodemographic data, as well as a shortened version of the IIEF (five items). Venous blood samples were collected. Total testosterone (TT), estradiol (E2), sex hormone-binding globulin (SHBG), dehydroepiandrosterone sulfate (DHEAS), total cholesterol (ChT), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), fasting plasma glucose (FPG) and albumin were determined. Lipid accumulation product (LAP) and visceral adiposity index (VAI) were calculated.
A correlation was found in the analysis of LAP index values (OR = 1.017; = 0.050). The analysis of hormone concentrations showed a correlation between the diagnosed trait and the value of TT (OR = 1.216; = 0.046) and SHBG (OR = 1.020; = 0.007).
VAI and LAP have been shown to be good indicators for assessing erectile dysfunction in men over 60 years of age.
本研究旨在分析男性国际勃起功能指数（IIEF）问卷诊断的勃起功能障碍（ED）患病率与相应性激素和生化参数水平、内脏脂肪堆积和活性指标之间的关系。
本研究纳入了来自波兰什切青市初级保健门诊的 148 名男性（60-75 岁）患者。要求男性填写一份包含社会人口学数据和 IIEF（五项）简短版本的简化调查问卷。采集静脉血样。测定总睾酮（TT）、雌二醇（E2）、性激素结合球蛋白（SHBG）、硫酸脱氢表雄酮（DHEAS）、总胆固醇（ChT）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、甘油三酯（TG）、空腹血糖（FPG）和白蛋白。计算脂质蓄积产物（LAP）和内脏脂肪指数（VAI）。
在 LAP 指数值的分析中发现了相关性（OR=1.017；=0.050）。激素浓度分析显示，诊断特征与 TT（OR=1.216；=0.046）和 SHBG（OR=1.020；=0.007）值之间存在相关性。
VAI 和 LAP 已被证明是评估 60 岁以上男性勃起功能障碍的良好指标。
