Department of Psychiatry, Tri-Service General Hospital Beitou Branch, National Defense Medical Center, Taipei City 112, Taiwan.
Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei City 114, Taiwan.
Int J Environ Res Public Health. 2022 Jul 1;19(13):8087. doi: 10.3390/ijerph19138087.
This study aimed to investigate the association between the heat-related illness (HRI) and the risk of developing psychiatric disorders. From 2000 to 2015, there were 3126 patients with newly diagnosed HRI selected from the National Health Insurance Research Database, along with 31,260 controls matched for gender and age. Fine and Gray’s analysis was used to compare the risk of psychiatric disorders during the 16 years of follow-up. Among the subjects, 523 of the HRI patients and 3619 of the control group (1774.18 vs. 1193.78 per 100,000 person-years) developed psychiatric disorders. Compared with non-HRI patients, the HRI ones had a 3.849-fold risk of being attacked by psychiatric disorders (95% CI: 3.632−4.369, p < 0.001) after adjusting for potential confounders. The sensitivity analysis revealed that the relationship between the HRI and the listed psychiatric disorders was determined by the exclusion of the first-year psychiatric events after the HRI. In spite of deleting the psychiatric diagnoses of the first five years, the HRI was still correlated with the development of psychiatric disorders with the exception of schizophreniform disorders, posttraumatic stress disorders, and acute stress disorder. Therefore, our findings concluded that the HRI could be a potential influence on the increased hazard of psychiatric disorders.
本研究旨在探讨与热相关疾病（HRI）与精神障碍风险之间的关联。从 2000 年到 2015 年，从国家健康保险研究数据库中选择了 3126 例新诊断的 HRI 患者，并与性别和年龄相匹配的 31260 名对照进行了匹配。Fine 和 Gray 的分析用于比较 16 年随访期间精神障碍的风险。在这些受试者中，HRI 患者中有 523 例和对照组中有 3619 例（1774.18 比 1193.78/100000 人年）发展为精神障碍。与非 HRI 患者相比，HRI 患者发生精神障碍的风险高出 3.849 倍（95%CI：3.632−4.369，p<0.001），校正了潜在混杂因素后。敏感性分析表明，HRI 与列出的精神障碍之间的关系取决于排除 HRI 后第一年的精神事件。尽管删除了 HRI 后五年的精神诊断，但除分裂样障碍、创伤后应激障碍和急性应激障碍外，HRI 仍与精神障碍的发展相关。因此，我们的研究结果表明，HRI 可能是增加精神障碍风险的一个潜在影响因素。
