Poli Pier Paolo, Jesus Laís Kawamata de, Dayube Ulisses Ribeiro Campos, Hadad Henrique, Loureiro Caroline, Chiba Fernando Yamamoto, Furtado Thayane Silveira Mata, Silva Maísa Pereira, Okamoto Roberta, Maiorana Carlo, Carvalho Paulo Sergio Perri de, Souza Francisley Ávila
Implant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Materials (Basel). 2022 Jun 21;15(13):4371. doi: 10.3390/ma15134371.
(1) Background: This study evaluates the effects of photobiomodulation (PBM) therapy on the peri-implant bone healing of implants with a machined surface (MS) and treated surface (TS). (2) Methods: Topographic characterization of the surfaces (scanning electron microscopy [SEM]- energy dispersive X-ray spectroscopy [EDX]) was performed before and after implant removal. Twenty rabbits were randomly divided into four groups: MS and TS groups (without PBM therapy) and LMS and LTS groups (with PBM therapy). After implant placement, the stability coefficient (ISQ) was measured. In the periods of 21 and 42 days, the ISQ was measured again, followed by biomechanical analysis. (3) Results: The surfaces of the TS implants showed topographic differences compared with MS implants. The ISQ values of the LMS were statistically significant when compared with those of the MS at 42 days (p < 0.001). The removal torque values of the LMS were statistically significant when compared with those of the MS at 21 days (p = 0.023) and 42 days (p = 0.023). For SEM, in general, the LMS, TS and LTS presented high bone tissue coverage when compared to MS. (4) Conclusions: The PBM therapy modulated the osseointegration process and was evidenced mainly on the machined surface.
(1) 背景：本研究评估光生物调节（PBM）疗法对具有机械加工表面（MS）和处理表面（TS）的种植体周围骨愈合的影响。(2) 方法：在种植体取出前后对表面进行形貌表征（扫描电子显微镜[SEM] - 能量色散X射线光谱[EDX]）。将20只兔子随机分为四组：MS组和TS组（无PBM疗法）以及LMS组和LTS组（有PBM疗法）。种植体植入后，测量稳定性系数（ISQ）。在21天和42天时，再次测量ISQ，随后进行生物力学分析。(3) 结果：与MS种植体相比，TS种植体的表面显示出形貌差异。在42天时，LMS组的ISQ值与MS组相比具有统计学意义（p < 0.001）。在21天（p = 0.023）和42天（p = 0.023）时，LMS组的取出扭矩值与MS组相比具有统计学意义。对于SEM，总体而言，与MS相比，LMS、TS和LTS呈现出高骨组织覆盖率。(4) 结论：PBM疗法调节了骨整合过程，主要在机械加工表面得到证实。
