Synthesis and Characterization of Catechol-Containing Polyacrylamides with Adhesive Properties.

In this study, a row of four analogous dopamine acryl- and methacrylamide derivatives, namely -(3,4-dihydroxyphenyethyl) acrylamide, -(3,4-dihydroxyphenyethyl) meth acrylamide, -phenethyl methacrylamide, -(4-hydroxyphenethyl) methacrylamide were synthesized and characterized by H-NMR and C-NMR, followed by further solvent-based radical polymerization with -hydroxyethyl acrylamide. All copolymers were characterized by H-NMR, dynamic differential calorimetry, and gel permeation chromatography. The dependency of the used comonomer ratios to the molecular mass of the corresponding copolymers has been described. The synthesis of the various polymers serves as a feasibility study and provides important data for a future biometric application in the medical field. We synthesized -(3,4-dihydroxyphenyethyl) acrylamide copolymer up to 80 mol% by free radical polymerization without using any protecting groups. All polymers show identical perfect adhesive properties by a simple scratch test. Further, the monomers were used as a photo reactive glue formulation to test its adherence to a medical titanium surface sample by tensile shear test.