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及其成分的抗菌、抗真菌、抗病毒和抗寄生虫活性:综述。

Antibacterial, Antifungal, Antiviral, and Antiparasitic Activities of and Its Ingredients: A Review.

机构信息

The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

出版信息

Molecules. 2022 Jun 29;27(13):4161. doi: 10.3390/molecules27134161.

Abstract

Infectious diseases have always been the number one enemy threatening health and well-being. With increasing numbers of infectious diseases, growing resistance of pathogens, and declining roles of antibiotics in the treatment of infectious diseases, it is becoming increasingly difficult to treat new infectious diseases, and there is an urgent need to develop new antibiotics to change the situation. Natural products tend to exhibit many special biological properties. The genus (Zygophyllaceae) has been used, for a long time, to treat cough, asthma, lumbago, hypertension, diabetes, and Alzheimer's disease. Over the past two decades, a growing number of studies have shown that components from Linn and its derivatives can inhibit a variety of microorganisms by inducing the accumulation of ROS in microorganisms, damaging cell membranes, thickening cell walls, disturbing cytoplasm, and interfering with DNA synthesis. In this paper, we provide a review on the antibacterial, antifungal, antiviral, and antiparasitic activities of , with a view to contribute to research on utilizing for medicinal applicaitons and to provide a reference in the field of antimicrobial and a basis for the development of natural antimicrobial agents for the treatment of infectious diseases.

摘要

传染病一直是威胁健康和福祉的头号敌人。随着传染病数量的增加、病原体耐药性的增强以及抗生素在传染病治疗中的作用下降,治疗新的传染病变得越来越困难,迫切需要开发新的抗生素来改变这种局面。天然产物往往表现出许多特殊的生物特性。(蒺藜科)属植物长期以来一直被用于治疗咳嗽、哮喘、腰痛、高血压、糖尿病和老年痴呆症。在过去的二十年中,越来越多的研究表明,来自 Linn 及其衍生物的成分可以通过在微生物中诱导 ROS 的积累来抑制多种微生物,破坏细胞膜、加厚细胞壁、扰乱细胞质并干扰 DNA 合成。本文综述了 的抗菌、抗真菌、抗病毒和抗寄生虫活性,以期为利用 进行药用研究做出贡献,并为抗菌领域提供参考,为治疗传染病的天然抗菌剂的开发提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a08a/9268262/5a04f0d931c7/molecules-27-04161-g001.jpg

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