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英格兰急性医院和救护信托机构中每日对 SARS-CoV-2 接触者进行检测的试点评估。

An evaluation of a pilot of daily testing of SARS-CoV-2 contacts in acute hospital and ambulance trusts in England.

机构信息

NHS Test and Trace, Department of Health and Social Care, UK.

NHS Test and Trace, Department of Health and Social Care, UK.

出版信息

Public Health. 2022 Aug;209:46-51. doi: 10.1016/j.puhe.2022.05.013. Epub 2022 Jun 8.

Abstract

OBJECTIVES

Healthcare worker (HCW) SARS-CoV-2 contacts in England have been required to quarantine, creating staff shortages. We piloted daily contact testing (DCT) to assess its feasibility as an alternative.

STUDY DESIGN

Observational service evaluation.

METHODS

We conducted an observational service evaluation of 7-day DCT using antigen lateral flow devices (LFDs) at four acute hospital trusts and one ambulance trust in England. Mixed methods were used, using aggregate and individual-level test monitoring data, semi-structured interviews, and a survey of eligible contacts.

RESULTS

In total, 138 HCWs were identified as contacts of a confirmed SARS-CoV-2 case. Of these, 111 (80%) consented to daily LFD testing, of whom 82 (74%) completed the required programme without interruption and 12 (11%) completed with interruption. Fifty-eight participants (52%) and two non-participants (7.4%) completed the survey. In total, 28 interviews were conducted with participants, site and infection control leads, and union representatives. One participant tested positive on LFD and polymerase chain reaction (PCR) test. Three participants tested positive on PCR but not LFD. DCT was well-accepted by trusts and staff. Participants reported no relaxation of their infection prevention and control behaviours. No incidents of transmission were detected. An estimated 729 potential days of work absence were averted.

CONCLUSIONS

DCT can be acceptably operated in a healthcare setting, averting quarantine-related work absences in HCW SARS-CoV-2 contacts.

摘要

目的

在英国,医护人员 (HCW) 的 SARS-CoV-2 接触者被要求进行隔离,从而导致人员短缺。我们试行每日接触检测 (DCT),以评估其作为替代方案的可行性。

研究设计

观察性服务评估。

方法

我们在英格兰的四家急性医院信托和一家救护车信托机构中,使用抗原侧向流动设备 (LFD) 对 7 天 DCT 进行了观察性服务评估。采用了混合方法,使用聚合和个体水平的测试监测数据、半结构化访谈以及对合格接触者的调查。

结果

总共确定了 138 名 HCW 作为确诊 SARS-CoV-2 病例的接触者。其中,111 人(80%)同意进行每日 LFD 检测,其中 82 人(74%)无中断地完成了所需的方案,12 人(11%)有中断地完成了方案。58 名参与者(52%)和两名非参与者(7.4%)完成了调查。共进行了 28 次访谈,涉及参与者、现场和感染控制负责人以及工会代表。一名参与者的 LFD 和聚合酶链反应 (PCR) 检测呈阳性。三名参与者的 PCR 检测呈阳性,但 LFD 检测呈阴性。DCT 受到信托和员工的广泛接受。参与者报告称他们没有放松感染预防和控制行为。未发现传播事件。估计避免了 729 个潜在的工作日缺勤。

结论

DCT 可在医疗保健环境中可接受地运行,避免了 SARS-CoV-2 接触者的 HCW 因隔离而导致的工作缺勤。

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