Nanobiotechnology Department, New Technologies Research Group, Pasteur Institute of Iran, Tehran, Iran.
Faculty of Chemistry, Department of Inorganic Chemistry, University of Tabriz, Tabriz, Iran.
Int J Biol Macromol. 2022 Sep 30;217:1-18. doi: 10.1016/j.ijbiomac.2022.07.016. Epub 2022 Jul 6.
There is a growing demand for biomaterials developing with novel properties for biomedical applications hence, hydrogels with 3D crosslinked polymeric structures obtained from natural polymers have been deeply inspected in this field. Pectin a unique biopolymer found in the cell walls of fruits and vegetables is extensively used in the pharmaceutical, food, and textile industries due to its ability to form a thick gel-like solution. Considering biocompatibility, biodegradability, easy gelling capability, and facile manipulation of pectin-based biomaterials; they have been thoroughly investigated for various potential biomedical applications including drug delivery, wound healing, tissue engineering, creation of implantable devices, and skin-care products.
由于对用于生物医学应用的具有新型特性的生物材料的需求不断增长，因此，人们对由天然聚合物获得的具有 3D 交联聚合物结构的水凝胶进行了深入研究。果胶是一种存在于水果和蔬菜细胞壁中的独特生物聚合物，由于其能够形成浓稠的凝胶状溶液，因此被广泛应用于制药、食品和纺织行业。考虑到生物相容性、可生物降解性、易于胶凝的能力以及易于操作的基于果胶的生物材料；它们已经被彻底研究用于各种潜在的生物医学应用，包括药物输送、伤口愈合、组织工程、可植入设备的制造和皮肤护理产品。
