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外周灌注指数:剖宫产术后脊髓低血压的预测指标。

Peripheral Perfusion Index: A Predictor of Post-Spinal Hypotension in Caesarean Section.

作者信息

M G Nandini, Srinivasaiah Madhu, Prabhat K S Jyosthna, V Chaitra, Kuradagi Monica, Mulla Reshma, Murthy K T Venkatesh

机构信息

Anaesthesiology, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Bangalore, IND.

出版信息

Cureus. 2022 Jun 6;14(6):e25699. doi: 10.7759/cureus.25699. eCollection 2022 Jun.

Abstract

Background Early prediction of hypotension helps to decide appropriate prophylactic measures and, hence, safe anaesthesia for mothers and improved neonatal outcomes. Perfusion index (PI) measured from a standard pulse oximeter has shown positive results in the prediction of hypotension. This study aims to determine if PI can equally predict hypotension in parturients after administration of spinal anaesthesia at different time points. Methods Parturients posted for elective caesarean section belonging to the American Society of Anesthesiology II (ASA II) were divided into two groups based on baseline PI as group A <3.5 and group B ≥3.5. Fifty-six parturients were enrolled in the study. PI and blood pressure were monitored at baseline, every two minutes for 12 minutes and every five minutes until the end of the surgery, after administration of spinal anaesthesia with hyperbaric bupivacaine 10 mg. Incidence of hypotension was compared between groups at all time points of observation. Spearman's rank correlation coefficient was determined to check the correlation between baseline PI and the number of episodes of hypotension. Receiver operating characteristic (ROC) curve was plotted to determine the ideal cut-off at different time points. Results Baseline PI significantly correlated with the number of episodes of hypotension (r-0.525). The overall incidence of hypotension was significantly higher in parturients with baseline PI ≥3.5 (79.16%) as compared to those with PI <3.5 (33.33%). The incidence of hypotension at sixth, 10th and 37th minutes post-spinal anaesthesia administration was significantly higher in the group with PI ≥3.5. The sensitivity and specificity for the 3.5 cut-off of PI were 85.7% and 60%, respectively, at the 6th and 10th minute after spinal administration. A higher cut-off of 3.9 increases the specificity to 69% without much change in the sensitivity. Conclusion  Parturients with PI >3.9 at baseline have a higher risk of hypotension in the initial 10-12 minutes following spinal anaesthesia during caesarean delivery.

摘要

背景 低血压的早期预测有助于确定适当的预防措施,从而为产妇提供安全的麻醉并改善新生儿结局。通过标准脉搏血氧仪测量的灌注指数(PI)在低血压预测方面已显示出阳性结果。本研究旨在确定PI在不同时间点给予脊麻后的产妇中是否同样能预测低血压。方法 将拟行择期剖宫产的美国麻醉医师协会II级(ASA II)产妇根据基线PI分为两组,A组<3.5,B组≥3.5。56名产妇纳入本研究。在给予10 mg重比重布比卡因脊麻后,于基线、给药后每2分钟监测12分钟、之后每5分钟直至手术结束,监测PI和血压。在所有观察时间点比较两组间低血压的发生率。计算Spearman等级相关系数以检验基线PI与低血压发作次数之间的相关性。绘制受试者工作特征(ROC)曲线以确定不同时间点的理想临界值。结果 基线PI与低血压发作次数显著相关(r = -0.525)。基线PI≥3.5的产妇低血压总体发生率(79.16%)显著高于PI<3.5的产妇(33.33%)。PI≥3.5组在脊麻给药后第6、10和37分钟时低血压发生率显著更高。脊麻给药后第6和10分钟时,PI临界值为3.5时的敏感性和特异性分别为85.7%和60%。临界值提高到3.9时,特异性提高到69%,而敏感性变化不大。结论 基线PI>3.9的产妇在剖宫产脊麻后的最初10 - 12分钟内发生低血压的风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65fe/9270080/59bb7e0e135b/cureus-0014-00000025699-i01.jpg

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