Inamanamelluri Rachana, Das Saswati, Senapati Laxman K, Pradhan Amit
Anesthesiology, Mamata Medical College, Khammam, IND.
Anaesthesiology, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.
Cureus. 2022 Oct 18;14(10):e30431. doi: 10.7759/cureus.30431. eCollection 2022 Oct.
Background Hypotension is commonly encountered in patients undergoing lower-segment cesarean section (LSCS) under the subarachnoid block (SAB) owing to decreased vascular resistance caused by the sympathetic blockade and decreased cardiac output because of blood pooling in blocked areas of the body. Perfusion index (PI) is a good indicator of systemic vascular resistance and can foretell hypotension. This study aimed to associate baseline PI with intraoperative hypotension after SAB in LSCS. Methodology This was a prospective observational study with a sample size of 50. The baseline PI was recorded every 10 seconds for one minute in a supine position on the right index finger at room temperature of 26°C to 28°C. The blood pressure (BP) and heart rate (HR) were recorded at an interval of one minute for three minutes. The mean of PI, BP, and HR were taken as the preoperative value. Spinal anesthesia was administered as per institutional protocol. Hypotension, defined as mean arterial pressure (MAP) <20% of baseline or MAP <60 mmHg was treated with vasopressors. Regression analysis with the Spearman correlation coefficient was done to correlate PI and hypotension. Results The incidence of hypotension in parturients with PI <2.85 was 28.6% (5/20) and in parturients with PI >2.85 was 82.8% (p < 0.001). The requirement of sympathomimetics was higher in parturients with PI >2.85.The area under the receiver operating characteristic curve was 0.8883. A cut-off PI value of 2.85 can identify parturients at risk for central neuraxial block-induced hypotension with a sensitivity of 80% and a specificity of 75% (p < 0.001). Conclusions The PI is a useful tool for predicting hypotension in healthy parturients undergoing elective cesarean section under SAB.
在蛛网膜下腔阻滞(SAB)下行下段剖宫产术(LSCS)的患者中,由于交感神经阻滞导致血管阻力降低以及身体阻滞部位血液淤积致使心输出量减少,低血压较为常见。灌注指数(PI)是全身血管阻力的良好指标,能够预测低血压。本研究旨在探讨LSCS中SAB后基线PI与术中低血压的相关性。方法:这是一项前瞻性观察性研究,样本量为50例。在26°C至28°C室温下,患者仰卧位,于右手食指每隔10秒记录1分钟的基线PI。每隔1分钟记录3分钟的血压(BP)和心率(HR)。取PI、BP和HR的平均值作为术前值。按照机构方案实施脊髓麻醉。低血压定义为平均动脉压(MAP)<基线值的20%或MAP<60 mmHg,使用血管升压药进行治疗。采用Spearman相关系数进行回归分析,以关联PI与低血压。结果:PI<2.85的产妇低血压发生率为28.6%(5/20),PI>2.85的产妇低血压发生率为82.8%(p<0.001)。PI>2.85的产妇对拟交感神经药的需求更高。受试者工作特征曲线下面积为0.8883。PI临界值为2.85时,可识别出有中枢神经轴阻滞诱导低血压风险的产妇,敏感性为80%,特异性为75%(p<0.001)。结论:PI是预测在SAB下行择期剖宫产术的健康产妇低血压的有用工具。