Anand Corinna, Kranz Ragna-Marie, Husain Sarah, Koeder Christian, Schoch Nora, Alzughayyar Dima-Karam, Gellner Reinhold, Hengst Karin, Englert Heike
Faculty of Medicine, University of Muenster (WWU), Muenster, Germany.
Department of Food, Nutrition and Facilities, University of Applied Sciences Muenster, Muenster, Germany.
BMJ Nutr Prev Health. 2022 Feb 22;5(1):44-54. doi: 10.1136/bmjnph-2021-000340. eCollection 2022.
The potential of adopting a healthy lifestyle to fight non-communicable diseases (NCDs) is not fully used. We hypothesised that the Healthy Lifestyle Community Programme (HLCP, cohort 1) reduces weight and other risk markers compared with baseline and control.
24-month, non-randomised, controlled intervention trial. Intervention: intensive 8-week phase with seminars, workshops and coaching focusing on a healthy lifestyle (eg, plant-based diet, physical activity, stress management) and group support followed by a 22-month alumni phase. Weight reduction as the primary outcome and other NCD risk parameters were assessed at six time points. Participants were recruited from the general population. Multiple linear regression analyses were conducted.
143 participants (58±12 years, 71% female) were enrolled (91 in the intervention (IG) and 52 in the control group (CG)). Groups' baseline characteristics were comparable, except participants of IG were younger, more often females, overweight and reported lower energy intake (kcal/day). Weight significantly decreased in IG at all follow-ups by -1.5 ± 1.9 kg after 8 weeks to -1.9 ± 4.0 kg after 24 months and more than in CG (except after 24 months). Being male, in the IG or overweight at baseline and having a university degree predicted more weight loss. After the intervention, there were more participants in the IG with a 'high' adherence (+12%) to plant-based food patterns. The change of other risk parameters was most distinct after 8 weeks and in people at elevated risk. Diabetes-related risk parameters did not improve.
The HLCP was able to reduce weight and to improve aspects of the NCD risk profile. Weight loss in the IG was moderate but maintained for 24 months. Participants of lower educational status might benefit from even more practical units. Future interventions should aim to include more participants at higher risk.
DRKS00018821.
采用健康生活方式来对抗非传染性疾病（NCDs）的潜力尚未得到充分利用。我们假设健康生活方式社区项目（HLCP，队列1）与基线水平及对照组相比，能够减轻体重并降低其他风险指标。
为期24个月的非随机对照干预试验。干预措施：为期8周的强化阶段，包括研讨会、工作坊及指导，重点关注健康生活方式（如植物性饮食、体育活动、压力管理）及团体支持，随后是为期22个月的校友阶段。在六个时间点评估体重减轻情况作为主要结局以及其他非传染性疾病风险参数。参与者从普通人群中招募。进行了多元线性回归分析。
共纳入143名参与者（年龄58±12岁，71%为女性）（干预组91名，对照组52名）。两组的基线特征具有可比性，但干预组参与者更年轻，女性比例更高，超重且报告的能量摄入量（千卡/天）更低。干预组在所有随访中体重均显著下降，8周后下降了-1.5±1.9千克，24个月后下降了-1.9±4.0千克，且下降幅度大于对照组（24个月后除外）。男性、处于干预组、基线时超重以及拥有大学学位预测体重减轻更多。干预后，干预组中有更多参与者对植物性食物模式具有“高”依从性（增加12%）。其他风险参数的变化在8周后以及高危人群中最为明显。与糖尿病相关的风险参数未得到改善。
HLCP能够减轻体重并改善非传染性疾病风险状况的某些方面。干预组的体重减轻幅度适中，但维持了24个月。教育程度较低的参与者可能会从更具实践性的单元中受益。未来的干预措施应旨在纳入更多高危参与者。
DRKS00018821。
