Haddad Joud, Hasan Fouz, Roumeih Abdel Halim, Omar Abdullah
Department of Dermatology, Tishreen University, Latakia, Syria.
Department of Dermatology, Damascus, Syria.
Heliyon. 2022 Jun 30;8(7):e09816. doi: 10.1016/j.heliyon.2022.e09816. eCollection 2022 Jul.
The prevalence of anogenital warts caused by HPV has been on the rise in the war-torn country of Syria recently. Although physically mildly symptomatic, this disease has a considerable negative psychological effect on patients. This study showed up to reveal information on the quality of life (QoL) of these patients and its connection to age, gender, disease severity, educational level and marital status.
The study sample consisted of 57 males and 45 females aged between 18 and 64 years old. The patients were recruited from the main university hospital in Latakia, Syria. The assessment was done using two questionnaires: EQ-5D and CECA10.
The data from the EQ-5D revealed no problems in Mobility, Self-care or Usual Activities. Whereas, our study showed extreme levels of anxiety and depression in roughly 50% of the sample. A noticeable impact was seen in 31% of participants describing moderate pain and discomfort. The CECA10 questionnaire revealed an average of disease-specific QoL of 2.48 which indicates a moderate to severe impact. We noticed a statistically significant relationship between the QoL and the patient's age. The age group of 20-29 has suffered the most. Without statistical significance, the psychological burden was at its worst in single patients with severe disease and a high level of education. Females suffered a slightly worse emotional impact compared to males.
This study proved a negative effect of genital warts on patients mainly young educated individuals, females and severe cases.
近期，在饱受战争蹂躏的叙利亚，由人乳头瘤病毒（HPV）引起的肛门生殖器疣患病率呈上升趋势。尽管这种疾病在身体上症状较轻，但对患者有相当大的负面心理影响。本研究旨在揭示这些患者的生活质量（QoL）信息及其与年龄、性别、疾病严重程度、教育水平和婚姻状况的关系。
研究样本包括57名男性和45名女性，年龄在18至64岁之间。患者从叙利亚拉塔基亚的主要大学医院招募。使用两份问卷进行评估：EQ - 5D和CECA10。
EQ - 5D的数据显示在行动能力、自我护理或日常活动方面没有问题。然而，我们的研究表明，大约50%的样本存在极度焦虑和抑郁。31%的参与者表示有中度疼痛和不适，这产生了明显影响。CECA10问卷显示特定疾病的生活质量平均为2.48，表明有中度至重度影响。我们注意到生活质量与患者年龄之间存在统计学上的显著关系。20 - 29岁年龄组受影响最大。在单患重病且教育水平高的患者中，心理负担最严重，但无统计学意义。与男性相比，女性的情绪影响略差。
本研究证明生殖器疣对患者有负面影响，主要是年轻的受过教育的个体、女性和重症患者。
