Blichmann C, Serup J
Contact Dermatitis. 1987 Mar;16(3):155-9. doi: 10.1111/j.1600-0536.1987.tb01411.x.
Transepidermal water loss (TEWL) and electrical conductance by a high-frequency (3.5 MHz) method were measured in 20 patients with chronic scaly hand eczema. Eczematous skin was compared with uninvolved skin of the same anatomical region. TEWL of eczematous skin was increased in all patients. In contrast, the conductance was decreased in all patients except for one, who showed equal values in pathological and uninvolved skin. This indicates that the water-holding capacity of eczematous skin is reduced. There was no correlation between clinical grading of scaling, and TEWL and electrical conductance. TEWL and conductance were not correlated, and the 2 methods are therefore supplementary for assessment of eczema and scaling. TEWL may be useful for monitoring the primary effect of therapy, and conductance for the final documentation of healing.
采用高频（3.5兆赫）方法对20例慢性鳞屑性手部湿疹患者的经表皮水分流失（TEWL）和电导率进行了测量。将湿疹皮肤与其同一解剖区域未受累的皮肤进行比较。所有患者的湿疹皮肤TEWL均升高。相比之下，除1例患者病理皮肤和未受累皮肤电导率值相等外，其他所有患者的电导率均降低。这表明湿疹皮肤的持水能力降低。鳞屑的临床分级与TEWL和电导率之间无相关性。TEWL和电导率不相关，因此这两种方法在评估湿疹和鳞屑方面具有互补性。TEWL可能有助于监测治疗的主要效果，而电导率可用于愈合的最终记录。
