Serup J, Blichmann C
Department of Dermatology, Gentofte Hospital, Copenhagen, Denmark.
Acta Derm Venereol. 1987;67(4):357-9.
Seventy-seven plaques of ten patients with psoriasis vulgaris were studied with measurement of electrical conductance (3.5 MHz), measurement of transepidermal water loss (TEWL), and clinical scoring of erythema, induration and scaling. Uninvolved skin of the same body region served as control. Findings were very distinct with decreased conductance and increased TEWL. Plaques with no or mild scaling did not differ from grossly scaly plaques. Scales of psoriasis do not seem to exert any major occlusive effect on the water evaporation. The inverse relation between conductance and TEWL indicates reduced water-holding capacity of psoriatic epidermis, being a very common feature.
对10例寻常型银屑病患者的77个斑块进行了研究，测量了电导（3.5兆赫）、经表皮水分流失（TEWL），并对红斑、硬结和脱屑进行了临床评分。同一身体部位未受累的皮肤作为对照。研究结果非常明显，电导降低，TEWL增加。无脱屑或轻度脱屑的斑块与严重脱屑的斑块没有差异。银屑病的鳞屑似乎对水分蒸发没有任何主要的封闭作用。电导与TEWL之间的反比关系表明银屑病表皮的持水能力降低，这是一个非常常见的特征。
