液态烟熏稻壳纳米颗粒抑制牙龈卟啉单胞菌。
Nanoparticles of Liquid Smoke Rice Husk Inhibit Porphyromonas gingivalis.
作者信息
Arundina Ira, Diyatri Indeswati, Juliastuti Wisnu Setiari, Budhy Theresia Indah, Surboyo Meircurius Dwi Condro, Iskandar Benni, Halimah Anisa Nur, Moelyanto Azzahra Salsabila Adira, Ramaniasari Sheryn Marcha, Saputra Gustiadi
机构信息
Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Department of Oral Pathology and Maxillofacial, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
出版信息
Eur J Dent. 2023 May;17(2):337-341. doi: 10.1055/s-0042-1749154. Epub 2022 Jul 12.
OBJECTIVE
Utilization of liquid smoke rice husk can be used as an alternative treatment because of the antimicrobial properties. Advances in drug delivery systems are increasingly developing to increase the bioavailability of drugs and reduce the side effects of these drugs, namely nanoparticles. In this study, nanoparticles of liquid smoke rice husk (nLSRH) were tested the antimicrobial against .
MATERIALS AND METHOD
This type of research is an experimental laboratory using culture. nLSRH contained liquid smoke rice husk concentration of 1, 2.5, 5, 7.5, 10, 12.5, 15, and 17.5%. The antibacterial was performed using the dilution methods.
RESULTS
The nLRSH concentration of 1% showed clearest medium. The highest number of colonies was observed at nLSRH concentration of 1% (40.3 colony-forming unit [CFU]) and decreased at a concentration of 2.5% (11.3 CFU); other concentration or no bacterial colony growth was found. The nLSRH concentration of 2.5% can be determined as the minimum inhibitory concentration and nLSRH concentration of 5% can be determined as the minimum bactericidal concentration.
CONCLUSION
nLSRH have antimicrobial activity against . This finding able to drive the next research to develop nLSRH as gingival and periodontitis disease is caused by
目的
由于具有抗菌特性，稻壳烟熏液可作为一种替代治疗方法。药物递送系统的进展日益显著，以提高药物的生物利用度并减少这些药物的副作用，即纳米颗粒。在本研究中，对稻壳烟熏液纳米颗粒（nLSRH）进行了抗菌测试。
材料与方法
本研究类型为实验室实验研究，采用培养法。nLSRH含有浓度为1%、2.5%、5%、7.5%、10%、12.5%、15%和17.5%的稻壳烟熏液。采用稀释法进行抗菌测试。
结果
1%的nLRSH浓度显示培养基最清澈。在1%的nLSRH浓度下观察到的菌落数量最多（40.3个菌落形成单位[CFU]），在2.5%的浓度下菌落数量减少（11.3 CFU）；其他浓度下未发现细菌菌落生长。2.5%的nLSRH浓度可确定为最低抑菌浓度，5%的nLSRH浓度可确定为最低杀菌浓度。
结论
nLSRH对……具有抗菌活性。这一发现能够推动后续研究开发nLSRH，因为牙龈和牙周炎疾病是由……引起的
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