Boen-Tan T N, Stilma J S
Doc Ophthalmol. 1986 Dec 30;64(1):59-67. doi: 10.1007/BF00166686.
Short-term observation following Nd-YAG laser capsulotomy indicates that serious elevation of intra-ocular pressure may occur, unrelated to the amount of energy used. In this study the IOP in 3 groups of 10 pseudophakic patients undergoing Nd-YAG laser posterior capsulotomy was measured before capsulotomy and 2 and 4 hours afterwards, using the fellow-eye as control. The first group received no medication, the second received timolol 1/2% eyedrops preoperatively, the third group a combination of timolol 1/2% and 1 tablet of acetazolamide 250 mg systemically. Pretreatment with timolol 0.5% minimizes IOP-rise but does not give complete protection. The combination of timolol 0.5% with 1 tablet of acetazolamide 250 mg proves to be a safe procedure for the prevention of IOP-rise after YAG laser capsulotomy. To prevent other complications it is advisable to make a small capsulotomy of 2-3 mm diameter using as little energy as possible. Also a defocussing system in the laser is a great advantage. Indomethacin drops during a period of 6 weeks after Nd-YAG laser capsulotomy should prevent cystoid macular edema.
钕钇铝石榴石激光晶状体后囊切开术后的短期观察表明，可能会出现严重的眼压升高，这与所使用的能量大小无关。在本研究中，对3组每组10例接受钕钇铝石榴石激光后囊切开术的人工晶状体植入患者，在囊切开术前以及术后2小时和4小时测量眼压，以对侧眼作为对照。第一组未用药，第二组术前使用0.5%噻吗洛尔滴眼液，第三组使用0.5%噻吗洛尔滴眼液并口服1片250mg乙酰唑胺。术前用0.5%噻吗洛尔预处理可使眼压升高最小化，但不能提供完全保护。0.5%噻吗洛尔与1片250mg乙酰唑胺联合使用被证明是预防钕钇铝石榴石激光晶状体后囊切开术后眼压升高的安全方法。为预防其他并发症，建议使用尽可能少的能量进行直径2 - 3mm的小囊切开术。此外，激光中的散焦系统非常有利。钕钇铝石榴石激光晶状体后囊切开术后6周内使用吲哚美辛滴眼液可预防黄斑囊样水肿。
