伊洛沙星（E-3432）对临床分离株的体外抗菌活性。
In vitro antibacterial activity of irloxacin (E-3432) on clinical isolates.
作者信息
Coll R, Esteve M, Moros M, Xicota M A, Parés J
出版信息
Drugs Exp Clin Res. 1987;13(2):75-7.
PMID:3582134
Abstract
Irloxacin (E-3432) is a new quinolone derivative. In this study, the activity of irloxacin was compared with that of nalidixic acid, norfloxacin and ciprofloxacin against strains of clinical isolates. Irloxacin showed greater in vitro activity than nalidixic acid, similar activity to norfloxacin and lower activity than ciprofloxacin. Against Staphylococcus, the MIC range of E-3432 was 0.06-1 mg/l, better than the other compounds studied.
摘要
伊洛沙星（E-3432）是一种新型喹诺酮衍生物。在本研究中，比较了伊洛沙星与萘啶酸、诺氟沙星和环丙沙星对临床分离菌株的活性。伊洛沙星的体外活性比萘啶酸强，与诺氟沙星相似，比环丙沙星弱。对葡萄球菌而言，E-3432的最低抑菌浓度范围为0.06-1mg/l，优于所研究的其他化合物。
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