Kurth K H, Marquet R, Zwartendijk J, Warnaar S O
Eur Urol. 1987;13(1-2):103-9. doi: 10.1159/000472745.
33 patients with metastatic renal cell carcinoma were treated intradermally with an autologous (29 patients) or allogeneic (4 patients) irradiated tumor cell preparation mixed with Corynebacterium parvum given monthly after palliative nephrectomy (27 patients) or excision of tumor metastases (2 patients). No significant toxicity was produced. 8 patients (24%) underwent objective responses. Responding patients had a median survival of 32 months, the median survival of all patients was 17 months (differences not significant).
33例转移性肾细胞癌患者在姑息性肾切除术（27例）或肿瘤转移灶切除术后（2例），每月接受皮内注射自体（29例）或异体（4例）照射的肿瘤细胞制剂，该制剂与短小棒状杆菌混合使用。未产生明显毒性。8例患者（24%）出现客观反应。有反应的患者中位生存期为32个月，所有患者的中位生存期为17个月（差异无统计学意义）。
