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慢性乙醇处理对大鼠肝脏和心脏中过氧化物酶体酰基辅酶A氧化酶活性及脂质过氧化的影响。

Effect of chronic ethanol treatment on peroxisomal acyl-CoA oxidase activity and lipid peroxidation in rat liver and heart.

作者信息

Panchenko L F, Pirozhkov S V, Popova S V, Antonenkov V D

出版信息

Experientia. 1987 May 15;43(5):580-1. doi: 10.1007/BF02143593.

Abstract

Chronic ethanol administration was shown to increase catalase and acyl-CoA oxidase activities in rat myocardium but did not alter the activity of liver peroxisomal enzymes. As a result of alcohol consumption a 2-3-fold increase in the level of lipid peroxidation was observed in the heart tissue while in the liver the induction was much less pronounced.

摘要

长期给予乙醇可使大鼠心肌中的过氧化氢酶和酰基辅酶A氧化酶活性增加,但不会改变肝脏过氧化物酶体酶的活性。饮酒导致心脏组织中脂质过氧化水平增加2至3倍,而在肝脏中这种诱导作用则不那么明显。

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