An Zhenyi, Chiang Wei-Chung, Fernández Álvaro F, Franco Luis H, He CongCong, Huang Shu-Yi, Lee Eunmyong, Liu Yang, Sebti Salwa, Shoji-Kawata Sanae, Sirasanagandla Shyam, Wang Richard C, Wei Yongjie, Zhao Yuting, Vega-Rubin-de-Celis Silvia
Broad Institute of MIT and Harvard, Cambridge, MA, United States.
Institute of Biochemistry and Molecular Biology, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Front Cell Dev Biol. 2022 Jun 27;10:891332. doi: 10.3389/fcell.2022.891332. eCollection 2022.
With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.
科学界怀着巨大的悲痛，于2020年6月15日收到贝丝·莱文去世的消息。莱文博士是自噬领域的先驱，她实验室的工作不仅使人们对调控该通路的分子机制有了更深入的了解，还揭示了其在多种生理和病理状况中的意义，包括其在发育、宿主防御、肿瘤发生、衰老或代谢中的作用。本综述并非旨在全面阐述自噬，而是从她的一些学生的视角，概述贝丝·莱文团队所取得的部分发现，以期纪念她在科学界的遗产。
