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Low rate of subsequent malignant neoplasms after CD19 CAR T-cell therapy.

作者信息

Hsieh Emily M, Myers Regina M, Yates Bonnie, Annesley Colleen, John Samuel, Taraseviciute Agne, Steinberg Seth M, Sheppard Jennifer, Chung Perry, Chen Lee, Lee Daniel W, DiNofia Amanda, Grupp Stephan A, Verneris Michael R, Laetsch Theodore W, Bhojwani Deepa, Brown Patrick A, Pulsipher Michael A, Rheingold Susan R, Gardner Rebecca A, Gore Lia, Shah Nirali N, Lamble Adam J

机构信息

Division of Hematology/Oncology/Transplantation and Cellular Therapy, Children's Hospital Los Angeles Cancer and Blood Disease Institute, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Division of Oncology, Cell Therapy and Transplant Section, Children's Hospital of Philadelphia, Philadelphia, PA.

出版信息

Blood Adv. 2022 Sep 13;6(17):5222-5226. doi: 10.1182/bloodadvances.2022008093.

DOI:10.1182/bloodadvances.2022008093
PMID:35834728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9631644/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d74/9631644/c00b457ce4fd/advancesADV2022008093absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d74/9631644/c00b457ce4fd/advancesADV2022008093absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d74/9631644/c00b457ce4fd/advancesADV2022008093absf1.jpg

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Blood Adv. 2023 Feb 28;7(4):575-585. doi: 10.1182/bloodadvances.2022007423.
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Next-Generation Sequencing of Minimal Residual Disease for Predicting Relapse after Tisagenlecleucel in Children and Young Adults with Acute Lymphoblastic Leukemia.儿童和青年急性淋巴细胞白血病患者接受 tisagenlecleucel 治疗后,微小残留病的下一代测序预测复发。
Blood Cancer Discov. 2022 Jan;3(1):66-81. doi: 10.1158/2643-3230.BCD-21-0095. Epub 2021 Dec 1.
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Blinatumomab Nonresponse and High-Disease Burden Are Associated With Inferior Outcomes After CD19-CAR for B-ALL.
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Blood. 2024 Dec 12;144(24):2473-2481. doi: 10.1182/blood.2024025828.
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The Current Landscape of Secondary Malignancies after CAR T-Cell Therapies: How Could Malignancies Be Prevented?嵌合抗原受体 T 细胞疗法后继发性恶性肿瘤的现状:如何预防恶性肿瘤?
Int J Mol Sci. 2024 Sep 1;25(17):9518. doi: 10.3390/ijms25179518.
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Characterization of second primary malignancies post CAR T-cell therapy: real-world insights from the two global pharmacovigilance databases of FAERS and VigiBase.嵌合抗原受体(CAR)T细胞疗法后第二原发性恶性肿瘤的特征:来自FAERS和VigiBase这两个全球药物警戒数据库的真实世界见解
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