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胃原发性恶性黑色素瘤转移:一种罕见的临床表现并文献复习。

Metastatic primary gastric melanoma: a rare clinical presentation and a review of literature.

机构信息

Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

出版信息

BMJ Case Rep. 2022 Jul 14;15(7):e249312. doi: 10.1136/bcr-2022-249312.

Abstract

Primary gastric melanoma is a rare clinical finding. It presents with upper gastrointestinal symptoms like abdominal pain, weight loss and melaena. It is often difficult to differentiate a primary gastric melanoma from primary cutaneous melanoma with gastric metastasis. Upper gastrointestinal endoscopy and biopsy of the lesion for histopathology and immunohistochemistry help to reach a definite diagnosis. We report a case of primary gastric melanoma with metastases to the liver and bone. The patient was treated with palliative radiotherapy, palliative chemotherapy and a bone-stabilising agent.

摘要

原发性胃黑色素瘤是一种罕见的临床发现。它表现为上消化道症状,如腹痛、体重减轻和黑便。原发性胃黑色素瘤与原发性皮肤黑色素瘤伴胃转移往往难以区分。上消化道内镜检查和病变活检进行组织病理学和免疫组织化学检查有助于明确诊断。我们报告了一例原发性胃黑色素瘤伴肝和骨转移的病例。该患者接受了姑息性放疗、姑息性化疗和骨稳定剂治疗。

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本文引用的文献

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Epigastric Pain and Melena Induced by Primary Gastric Melanoma.原发性胃黑色素瘤引起的上腹痛和黑便
Clin Gastroenterol Hepatol. 2019 Aug;17(9):e104. doi: 10.1016/j.cgh.2018.07.014.
5
Multifocal Gastrointestinal Melanoma.多发性胃肠道黑色素瘤。
J Gastrointestin Liver Dis. 2019 Jun 1;28:237-240. doi: 10.15403/jgld-185.
6
Primary gastric melanoma: case report of a rare malignancy.原发性胃黑色素瘤:一例罕见恶性肿瘤的病例报告
Rare Tumors. 2015 Mar 27;7(1):5683. doi: 10.4081/rt.2015.5683. eCollection 2015 Feb 11.
8
Primary gastric melanoma: a diagnostic challenge.原发性胃黑色素瘤:一项诊断挑战。
J Gastrointest Cancer. 2014 Dec;45 Suppl 1:33-5. doi: 10.1007/s12029-013-9530-6.
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