Gomez R A, Campbell F, Savory J, Chevalier R L
Int J Pediatr Nephrol. 1987 Jan-Mar;8(1):21-4.
The effects of chelation therapy by intravenous and intraperitoneal administration of deferoxamine were compared during maintenance continuous ambulatory peritoneal dialysis (CAPD) in a child with end stage renal disease and hemosiderosis. We demonstrate that intraperitoneally administered deferoxamine is safer, more practical and efficient than weekly intravenously administered deferoxamine for the treatment of iron overload in the pediatric patient undergoing CAPD.
在一名终末期肾病合并血色素沉着症的儿童进行持续性非卧床腹膜透析(CAPD)期间,比较了静脉注射和腹腔内注射去铁胺进行螯合治疗的效果。我们证明,对于接受CAPD的儿科患者,腹腔内注射去铁胺在治疗铁过载方面比每周静脉注射去铁胺更安全、更实用且更有效。