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一名接种新冠疫苗患者的脑静脉血栓形成的疑难诊断

A Puzzling Diagnosis of Cerebral Vein Thrombosis in a COVID-19-Vaccinated Patient.

作者信息

Alsallamin Isaac, Somoza-Cano Francisco J, Zakarna Lara, Aggarwal Pearl, Karia Rusina, Bawwab Ameed, Chakhachiro Deema, Alsallamin Afnan

机构信息

Internal Medicine, Northeast Ohio Medical University, Rootstown, USA.

Internal Medicine, St. Vincent Charity Medical Center, Cleveland, USA.

出版信息

Cureus. 2022 Jun 11;14(6):e25860. doi: 10.7759/cureus.25860. eCollection 2022 Jun.

DOI:10.7759/cureus.25860
PMID:35836469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9273173/
Abstract

Cerebral vein thrombosis (CVT) is a rare condition equivalent to deep vein thrombosis of the intracranial veins. Delayed diagnosis will result in severe and disabling complications. We report a case of a 59-year-old man with CVT with no significant past medical or surgical history. On admission, he reported right-sided numbness and weakness concerns, preceded by the sudden onset of bilateral vision loss and dysarthria. Magnetic resonance imaging and computed tomography scans confirmed the diagnosis of CVT. The most interesting relative risk factor was flying overseas twice a month for the last 10 years; each flight was longer than eight hours. Another possible contributing factor to our patient's condition was polycythemia, with a hemoglobin level of 19, but the most questionable and puzzling is the recent coronavirus disease 2019 (COVID-19) vaccination two months, eight months, and one year prior to admission. Our case highlights a rare COVID-19 vaccine-related CVT diagnosis and that close monitoring for new symptoms and signs is vital to prevent life-threatening complications, herniation, and hemorrhagic transformation.

摘要

脑静脉血栓形成(CVT)是一种罕见疾病,等同于颅内静脉的深静脉血栓形成。延迟诊断会导致严重且致残的并发症。我们报告一例59岁男性CVT患者,其既往无重大内科或外科病史。入院时,他自述右侧麻木和无力,之前有突发双侧视力丧失和构音障碍。磁共振成像和计算机断层扫描确诊为CVT。最有意思的相关危险因素是在过去10年中每月两次飞往海外;每次飞行时间超过8小时。另一个可能导致我们患者病情的因素是红细胞增多症,血红蛋白水平为19,但最值得怀疑和令人困惑的是在入院前两个月、八个月和一年接种了新型冠状病毒肺炎(COVID-19)疫苗。我们的病例凸显了一种罕见的与COVID-19疫苗相关的CVT诊断,密切监测新的症状和体征对于预防危及生命的并发症、脑疝和出血性转化至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/d03f23dcfe7d/cureus-0014-00000025860-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/e8f0ffd24f9c/cureus-0014-00000025860-i01.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/d03f23dcfe7d/cureus-0014-00000025860-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/e8f0ffd24f9c/cureus-0014-00000025860-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/1efb4449e92c/cureus-0014-00000025860-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/dd69bfc1d7fa/cureus-0014-00000025860-i03.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/56b4c7153b1f/cureus-0014-00000025860-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/85feacc4341c/cureus-0014-00000025860-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe42/9273173/d03f23dcfe7d/cureus-0014-00000025860-i07.jpg

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Ischaemic stroke as a presenting feature of ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia.
缺血性中风作为ChAdOx1 nCoV-19疫苗诱导的免疫性血栓性血小板减少症的首发症状。
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