用于生物医学的一维微纳马达：递送、传感与手术

One-dimensional micro/nanomotors for biomedicine: delivery, sensing and surgery.

作者信息

Guo Jiawang, Lin Yuan

机构信息

The State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin Province, China.

出版信息

Biomater Transl. 2020 Dec 28;1(1):18-32. doi: 10.3877/cma.j.issn.2096-112X.2020.01.003. eCollection 2020.

DOI:10.3877/cma.j.issn.2096-112X.2020.01.003

PMID:35837656

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9255815/

Abstract

The rapid development of artificial micro/nanomachines brings promising strategies to overcome challenges in biomedicine, including delivery, sensing and surgery. One-dimensional (1D) micro/nanomotors are one of the most attractive micro/nanomachines due to their high specific surface area, powerful impetus and weak rotation diffusion. In this review, different propulsion mechanisms and motion control strategies of 1D micro/nanomotors are summarized, and recent efforts towards their fabrication methods and biomedical applications are discussed. We envision the multidisciplinary research efforts in the field of 1D micro/nanomotors will pave their way to practical applications in bioimaging and biomedicine.

摘要

人工微纳机器的快速发展为克服生物医学中的挑战带来了有前景的策略，包括递送、传感和手术。一维（1D）微纳马达因其高比表面积、强大的推动力和较弱的旋转扩散而成为最具吸引力的微纳机器之一。在这篇综述中，总结了一维微纳马达的不同推进机制和运动控制策略，并讨论了它们在制造方法和生物医学应用方面的最新进展。我们设想，一维微纳马达领域的多学科研究努力将为其在生物成像和生物医学中的实际应用铺平道路。