Department Safety in the Food Chain, German Federal Institute for Risk Assessment, Max-Dohrn-Straße 8-10, 10589 Berlin, Germany.
State Office for Nature, Environment and Consumer Protection (LANUV), North Rhine-Westphalia, 45659 Recklinghausen, Germany.
J Agric Food Chem. 2022 Jul 27;70(29):8955-8962. doi: 10.1021/acs.jafc.2c02243. Epub 2022 Jul 15.
Understanding the transfer of non-dioxin-like polychlorinated biphenyls (ndl-PCBs) into foods of animal origin is crucial for human health risk assessment. In two experiments, we investigated the transfer of ndl-PCBs from contaminated feed and soil into eggs and meat of laying hens. The transfer from the feed was investigated with 30 laying hens. The treated hens were divided into two groups fed a contaminated diet (12.8 μg/kg sum of indicator ndl-PCBs; 88% dry matter (DM)) for 28 and 63 days, respectively, and then experienced a depuration period of 100 days with control feed. The transfer from soil was investigated with 72 laying hens kept in three separate outdoor pens (with three levels of ndl-PCB soil contamination) for 168 days. In both experiments, eggs were collected and analyzed for ndl-PCBs. In the second experiment, animals ( = 3 at the beginning, = 6 per group after 42, 84, and 168 days) were slaughtered to determine ndl-PCBs in meat (breast muscle tissue) fat. The transfer of ndl-PCB from both feed and soil was clearly measurable and concentrations in eggs quickly exceeded maximum levels. Clear differences between individual congeners were observed. In particular, the low-chlorinated ndl-PCBs 52 and 101 are hardly found in eggs, despite their relatively high concentration in feed and soil. PCBs 138, 153, and 180, on the other hand, were found in large proportions in eggs and meat.
了解非二噁英多氯联苯（ndl-PCBs）向动物源食品中的转移对于人类健康风险评估至关重要。在两项实验中，我们研究了 ndl-PCBs 从受污染的饲料和土壤向产蛋母鸡的鸡蛋和肉中的转移。通过 30 只产蛋母鸡研究了从饲料中的转移。将处理过的母鸡分为两组，分别用受污染的饮食（指示性 ndl-PCBs 总量为 12.8 μg/kg；88%干物质（DM））喂养 28 和 63 天，然后用对照饮食进行 100 天的净化期。通过在三个单独的户外围栏中饲养的 72 只产蛋母鸡研究了从土壤中的转移（土壤中 ndl-PCB 污染水平分别为三个水平）168 天。在这两个实验中，收集鸡蛋并分析 ndl-PCBs。在第二个实验中，动物（开始时为 3 只，42、84 和 168 天后每组为 6 只）被屠宰以确定肉（胸肌组织）脂肪中的 ndl-PCBs。从饲料和土壤中转移 ndl-PCB 是可明显测量的，并且鸡蛋中的浓度很快超过了最大水平。观察到个体同系物之间存在明显差异。特别是，尽管低氯 ndl-PCBs 52 和 101 在饲料和土壤中的浓度相对较高，但它们在鸡蛋中几乎检测不到。另一方面，PCBs 138、153 和 180 大量存在于鸡蛋和肉中。
