Tyler Dr Elizabeth, Lobban Professor Fiona, Hadarag Mr Bogdan, Jones Professor Steven
Spectrum Centre for Mental Health Research, Division of Health Research, Lancaster University, Lancaster, UK.
Division of Health Research, Lancaster University, Lancaster, UK.
J Affect Disord Rep. 2022 Jul;9:100371. doi: 10.1016/j.jadr.2022.100371.
There is evidence to suggest that older people with Bipolar Disorder (BD) are more likely to demonstrate poor levels of functioning and score lower on well-being scales compared to non-clinical controls, even when in remission (Depp et al., 2006). To our knowledge, this is the first review paper to identify how quality of life and functioning has been measured in an older adult BD population.
We conducted a systematic review of studies including a quantitative measure of psychosocial functioning or quality of life and older people over the age of 50 with a formal diagnosis of BD I or II.
Eleven studies ( = 726, mean age range 59.8 to 71.1) were included in the review, demonstrating a significant lack of research in the area compered to younger people with BD. The most commonly used measure of functioning was the Global Assessment of Functioning Scale (GAF) and results indicated that older adults with BD demonstrate a wide range of functioning.
The review used a comprehensive and systematic search strategy, however, very few eligible studies were available for review. The pooled analyses and reported means must be interpreted with caution due to the relatively small sample sizes.
Older people with BD present with a wide range of functioning, ranging 'major impairment' to 'superior' scores. No existing validated measure assessing the psychosocial functioning or quality of life of older people with BD could be identified. Such a tool should be developed for use in future research.
有证据表明，与非临床对照人群相比，患有双相情感障碍（BD）的老年人即使在病情缓解期，其功能水平也更有可能较差，且在幸福感量表上得分更低（德普等人，2006年）。据我们所知，这是第一篇确定如何在老年双相情感障碍患者群体中测量生活质量和功能的综述文章。
我们对研究进行了系统综述，这些研究包括对心理社会功能或生活质量的定量测量，以及对50岁以上正式诊断为双相I型或II型障碍的老年人的研究。
该综述纳入了11项研究（n = 726，平均年龄范围为59.8至71.1岁），表明与年轻双相情感障碍患者相比，该领域的研究明显不足。最常用的功能测量方法是总体功能评估量表（GAF），结果表明双相情感障碍老年患者的功能范围很广。
该综述采用了全面且系统的检索策略，然而，可供综述的合格研究非常少。由于样本量相对较小，汇总分析和报告的均值必须谨慎解释。
双相情感障碍老年患者的功能范围很广，分数从“严重受损”到“优秀”不等。未发现现有的经过验证的评估双相情感障碍老年患者心理社会功能或生活质量的测量方法。应开发这样一种工具以供未来研究使用。
