York Daniel, Patel Pavan, Saikumar Smera
Colquitt Regional Medical Center, Sterling Center Women's Health, Moultrie GA 31768, USA.
Philadelphia College of Osteopathic Medicine, Moultrie, GA 31768, USA.
Case Rep Obstet Gynecol. 2022 Jul 7;2022:3109331. doi: 10.1155/2022/3109331. eCollection 2022.
In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. . A 48-year-old patient presented with a large fungating mass near her right inferior vulva with a hardness of surrounding tissues. The mass was 4 cm × 3 cm in size and was excised in the operating room. The pathology was negative for malignancy; however, it showed lymphoplasmacytic proliferation with immunostaining positive for HSV virus.
Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.
在罕见情况下，单纯疱疹病毒（HSV）感染可表现为假瘤，在未控制的HIV感染患者中常被误诊为恶性肿瘤。在合并感染HIV的个体中，2型单纯疱疹病毒（HSV - 2）感染率为60%至90%。一名48岁患者右下腹外阴附近出现一个巨大的蕈样肿块，周围组织质地硬。肿块大小为4厘米×3厘米，在手术室切除。病理检查排除恶性肿瘤；然而，显示有淋巴浆细胞增殖，免疫染色HSV病毒呈阳性。
对于出现生殖器肿块病变的免疫抑制患者，鉴别诊断时应考虑非典型HSV假瘤。
