与巨大阴茎蕈样肿物相关的单纯疱疹病毒2型

Herpes simplex virus-2 associated with a large fungating penile mass.

作者信息

Bowman Max S, Lang Ursula E, Leslie Kieron S, Amend Gregory, Breyer Benjamin N

机构信息

Department of Urology, University of California, San Francisco, Department of Urology, 400 Parnassus Ave, San Francisco, CA, 94143, USA.

Department of Pathology, Zuckerberg San Francisco General Hospital and University of California, San Francisco, 1001 Potrero Ave, San Francisco, CA, 94110, USA.

出版信息

Urol Case Rep. 2021 Feb 4;36:101594. doi: 10.1016/j.eucr.2021.101594. eCollection 2021 May.

DOI:10.1016/j.eucr.2021.101594

PMID:33604244

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7872973/

Abstract

A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy. Urology excised the mass and the defect was repaired primarily with good cosmetic result. Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration.

摘要

一名48岁的艾滋病毒/艾滋病男性患者，阴茎根部出现一个不断增大的结节性病变。组织学检查显示符合慢性病毒感染的变化，培养物中培养出单纯疱疹病毒2型（HSV-2）。该病变对伐昔洛韦和病灶内（IL）西多福韦治疗无效。泌尿外科切除了肿块，缺损主要通过一期修复，美容效果良好。术后病理证实为HSV-2，尽管病变外观不寻常，表现为结节状肿块且无明显溃疡。