Mahajan Rahul, Anand Kuljeet Singh, Juneja Abhishek, Garg Jyoti
Department of Neurology, Dr. RML Hospital, New Delhi, India.
Indian J Sex Transm Dis AIDS. 2022 Jan-Jun;43(1):72-74. doi: 10.4103/ijstd.IJSTD_91_19. Epub 2022 Jun 7.
Epstein-Barr virus (EBV) infection can rarely present as encephalitis in HIV patients. We report a case of a 22-year-old female patient, diagnosed to have HIV infection 8 years back. She presented with headache and altered behavior for a week and focal fits for 2 days. Neurological examination was unremarkable. Cerebrospinal fluid (CSF) examination revealed lymphocytic pleocytosis with raised protein. EBV was detected in CSF using polymerase chain reaction test. Magnetic resonance imaging of the brain revealed T2/fluid-attenuated inversion recovery hyperintensities involving the left frontal cortex, left thalamus, and right medial temporal cortex. The patient was started on antiviral therapy considering the diagnosis of EBV encephalitis. The patient completely recovered over the next few weeks.
爱泼斯坦-巴尔病毒（EBV）感染在艾滋病患者中很少表现为脑炎。我们报告一例22岁女性患者，8年前被诊断为感染艾滋病病毒。她出现头痛和行为改变一周，局灶性癫痫发作两天。神经系统检查无异常。脑脊液（CSF）检查显示淋巴细胞增多伴蛋白升高。使用聚合酶链反应试验在脑脊液中检测到EBV。脑部磁共振成像显示T2/液体衰减反转恢复序列高信号，累及左侧额叶皮质、左侧丘脑和右侧颞叶内侧皮质。考虑到EBV脑炎的诊断，患者开始接受抗病毒治疗。患者在接下来的几周内完全康复。
