黄连素邮票疗法成功治疗大疱性类天疱疮皮损：一例报告及文献复习
Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review.
作者信息
Cheng Linyan, Wang Yi, Lu Hanzhi, Guo Wanjun, Yan Ge, Zhu Jianyong, Guo Dongjie, Li Fulun
机构信息
Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
出版信息
Front Med (Lausanne). 2022 Jul 1;9:938761. doi: 10.3389/fmed.2022.938761. eCollection 2022.
Bullous pemphigoid (BP) is a life-threatening autoimmune disease of the skin that is mainly characterized by a large range of tension blisters and intense itching of the skin. The 1-year mortality rate of BP was 23.5%. Superinfection caused by skin lesion ulceration is one of the important causes of disease death. Therefore, it is challenging to control infection and improve skin wound healing. Here, we report the case of an elderly woman who presented with BP and involved the oral mucosa. The patient was successfully treated with hormones combined with topical berberine, and 95% of the patients' lesions healed completely after 1 month. In addition, we inductively analyzed the current treatments for BP to provide a reference for BP clinical treatment.
大疱性类天疱疮（BP）是一种危及生命的皮肤自身免疫性疾病，主要特征为出现大量张力性水疱和皮肤剧烈瘙痒。BP的1年死亡率为23.5%。皮肤病变溃疡引起的继发感染是疾病死亡的重要原因之一。因此，控制感染和促进皮肤伤口愈合具有挑战性。在此，我们报告一例患有BP且累及口腔黏膜的老年女性病例。该患者通过激素联合外用黄连素成功治愈，1个月后95%的皮损完全愈合。此外，我们归纳分析了目前BP的治疗方法，为BP的临床治疗提供参考。
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