When the Blisters Reach the Heart: An Uncommon Case of Cardiac Involvement in Bullous Pemphigoid.

Bullous pemphigoid is an autoimmune blistering disorder predominantly affecting the elderly, with rare systemic complications, including cardiac involvement. This case study presents a 46-year-old female with a history of arterial hypertension who developed complete heart block (CHB) associated with bullous pemphigoid. The patient initially presented with bilateral lower limb swelling and discoloration, later diagnosed as bullous pemphigoid following the appearance of characteristic skin lesions. Concurrently, she was found to have asymptomatic bradycardia, with an electrocardiogram confirming CHB. After ruling out other causes of heart block, a dual-chamber pacemaker was implanted, and the patient was treated with immunosuppressive therapy to control the autoimmune blistering disorder. This case highlights the rare but significant association between bullous pemphigoid and CHB, emphasizing the importance of multidisciplinary care and timely intervention in managing such complex cases.