MountainView Hospital, Las Vegas, NV, USA.
J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221111763. doi: 10.1177/23247096221111763.
Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical management, highest length of survival was reported to be 10 months. We report a case of malignant melanoma with isolated pancreatic metastasis treated with interferon therapy and immunotherapy, with evidence of progressive tumor shrinkage and survival at 38 months.
孤立性胰腺转移瘤来自黑色素瘤，其死亡率高，占转移性黑色素瘤的比例不到 1%。治疗方案有限，据报道，完全手术切除的患者总生存率最高。在文献中报告的非手术治疗病例中，最长的生存时间为 10 个月。我们报告了一例恶性黑色素瘤伴孤立性胰腺转移，接受干扰素治疗和免疫治疗，肿瘤有进展性缩小的证据，且患者存活 38 个月。
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