• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

24S-Hydroxycholesterol and Cerebellar Degeneration: Insights from SCA2.

作者信息

Locci Sara, Nidiaci Valentina, De Stefano Nicola, Leoni Valerio, Mignarri Andrea

机构信息

Unit of Neurology and Neurometabolic Diseases, Department of Medical, Surgical and Neurological Sciences, University of Siena, Viale Bracci 2, 53100, Siena, Italy.

Laboratory of Clinical Biochemistry, ASST-Brianza and Department of Medicine and Surgery, Hospital of Desio, University of Milano-Bicocca, Milan, Italy.

出版信息

Cerebellum. 2023 Oct;22(5):1020-1022. doi: 10.1007/s12311-022-01448-7. Epub 2022 Jul 18.

DOI:10.1007/s12311-022-01448-7
PMID:35851639
Abstract
摘要

相似文献

1
24S-Hydroxycholesterol and Cerebellar Degeneration: Insights from SCA2.24S-羟基胆固醇与小脑变性：来自脊髓小脑共济失调2型的见解
Cerebellum. 2023 Oct;22(5):1020-1022. doi: 10.1007/s12311-022-01448-7. Epub 2022 Jul 18.
2
24S-hydroxycholesterol: a marker of brain cholesterol metabolism.24S-羟基胆固醇：脑胆固醇代谢的标志物。
Pharmacopsychiatry. 2003 Sep;36 Suppl 2:S102-6. doi: 10.1055/s-2003-43053.
3
Accumulation of 24S-hydroxycholesterol in neuronal SK-N-BE cells treated with hexacosanoic acid (C26:0): argument in favor of 24S-hydroxycholesterol as a potential biomarker of neurolipotoxicity.用二十六烷酸（C26:0）处理的神经元SK-N-BE细胞中24S-羟基胆固醇的积累：支持24S-羟基胆固醇作为神经脂毒性潜在生物标志物的论据。
Rev Neurol (Paris). 2015 Feb;171(2):125-9. doi: 10.1016/j.neurol.2014.10.016. Epub 2015 Jan 8.
4
Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.血浆24S-羟基胆固醇：神经元变性的外周指标及阿尔茨海默病的潜在状态标志物。
Neuroreport. 2000 Jun 26;11(9):1959-62. doi: 10.1097/00001756-200006260-00030.
5
New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death.24(S)-羟基胆固醇在调节神经元细胞死亡中的新方面。
Free Radic Biol Med. 2015 Oct;87:366-72. doi: 10.1016/j.freeradbiomed.2015.06.036. Epub 2015 Jul 9.
6
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia.脑脊液中的24S-羟基胆固醇在痴呆症早期会升高。
J Psychiatr Res. 2002 Jan-Feb;36(1):27-32. doi: 10.1016/s0022-3956(01)00050-4.
7
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases.神经系统疾病患者的血浆24S-羟基胆固醇水平。
Neurosci Lett. 2000 Oct 27;293(2):87-90. doi: 10.1016/s0304-3940(00)01466-x.
8
Quantitative detection of free 24S-hydroxycholesterol, and 27-hydroxycholesterol from human serum.人血清中游离24S-羟基胆固醇和27-羟基胆固醇的定量检测。
BMC Neurosci. 2014 Dec 24;15:137. doi: 10.1186/s12868-014-0137-z.
9
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease.氧化固醇与帕金森病：脑脊液中 24S-羟基胆固醇水平与疾病持续时间相关的证据。
Neurosci Lett. 2013 Oct 25;555:102-5. doi: 10.1016/j.neulet.2013.09.003. Epub 2013 Sep 10.
10
Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients.痴呆患者血浆24S-羟基胆固醇和27-羟基胆固醇水平的改变
Neurosci Lett. 2004 Sep 30;368(3):303-8. doi: 10.1016/j.neulet.2004.07.031.

引用本文的文献

1
Longitudinal Changes of Clinical, Imaging, and Fluid Biomarkers in Preataxic and Early Ataxic Spinocerebellar Ataxia Type 2 and 7 Carriers.未病期和早期小脑共济失调型 2 型和 7 型脊髓小脑共济失调携带者的临床、影像学和液体生物标志物的纵向变化。
Neurology. 2024 Sep 10;103(5):e209749. doi: 10.1212/WNL.0000000000209749. Epub 2024 Aug 12.

本文引用的文献

1
The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer's Disease.24-S-羟基胆固醇在阿尔茨海默病中的争议性作用
Antioxidants (Basel). 2021 May 7;10(5):740. doi: 10.3390/antiox10050740.
2
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients.胆固醇代谢产物 27-羟胆固醇抑制 SARS-CoV-2，并且在 COVID-19 患者中明显降低。
Redox Biol. 2020 Sep;36:101682. doi: 10.1016/j.redox.2020.101682. Epub 2020 Aug 10.
3
Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia.
恢复大脑胆固醇周转率可改善自噬，并且在脊髓小脑共济失调的小鼠模型中具有治疗潜力。
Acta Neuropathol. 2019 Nov;138(5):837-858. doi: 10.1007/s00401-019-02019-7. Epub 2019 Jun 14.
4
Brain cholesterol metabolism and Parkinson's disease.脑胆固醇代谢与帕金森病。
Mov Disord. 2019 Mar;34(3):386-395. doi: 10.1002/mds.27609. Epub 2019 Jan 25.
5
Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.ataxin-2（Atxn2）基因敲除小鼠表现出支链氨基酸和脂肪酸途径改变。
Mol Cell Proteomics. 2016 May;15(5):1728-39. doi: 10.1074/mcp.M115.056770. Epub 2016 Feb 5.
6
The impairment of cholesterol metabolism in Huntington disease.亨廷顿舞蹈症中胆固醇代谢的损伤。
Biochim Biophys Acta. 2015 Aug;1851(8):1095-105. doi: 10.1016/j.bbalip.2014.12.018. Epub 2015 Jan 14.
7
Oxysterols and cholesterol precursors correlate to magnetic resonance imaging measures of neurodegeneration in multiple sclerosis.氧化固醇和胆固醇前体与多发性硬化症的神经退行性变的磁共振成像测量相关。
Mult Scler. 2014 Apr;20(4):412-7. doi: 10.1177/1352458513499421. Epub 2013 Aug 19.
8
Inventory of Non-Ataxia Signs (INAS): validation of a new clinical assessment instrument.非共济失调体征清单（INAS）：一种新的临床评估工具的验证。
Cerebellum. 2013 Jun;12(3):418-28. doi: 10.1007/s12311-012-0421-3.
9
24S-hydroxycholesterol in plasma: a marker of cholesterol turnover in neurodegenerative diseases.血浆 24S-羟基胆固醇：神经退行性疾病中胆固醇周转的标志物。
Biochimie. 2013 Mar;95(3):595-612. doi: 10.1016/j.biochi.2012.09.025. Epub 2012 Oct 3.
10
Pathoanatomy of cerebellar degeneration in spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3).脊髓小脑共济失调 2 型（SCA2）和 3 型（SCA3）小脑退行性变的病理解剖学。
Cerebellum. 2012 Sep;11(3):749-60. doi: 10.1007/s12311-011-0340-8.